F C Szoka
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Explore the profile of F C Szoka including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
753
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Recent Articles
1.
Structural studies of the monolayers and bilayers formed by a novel cholesterol-phospholipid chimera
Foglia F, Barlow D, Szoka F, Huang Z, Rogers S, Lawrence M
Langmuir
. 2011 Jun;
27(13):8275-81.
PMID: 21634402
Langmuir isotherm, neutron reflectivity, and small angle neutron scattering studies have been conducted to characterize the monolayers and vesicular bilayers formed by a novel chimeric phospholipid, ChemPPC, that incorporates a...
2.
Supattapone S, Wille H, Uyechi L, Safar J, Tremblay P, Szoka F, et al.
J Virol
. 2001 Mar;
75(7):3453-61.
PMID: 11238871
Branched polyamines, including polyamidoamine and polypropyleneimine (PPI) dendrimers, are able to purge PrP(Sc), the disease-causing isoform of the prion protein, from scrapie-infected neuroblastoma (ScN2a) cells in culture (S. Supattapone, H.-O....
3.
Choi S, Szoka F
Anal Biochem
. 2000 Jun;
281(1):95-7.
PMID: 10847615
A rapid and sensitive assay for the detection of deoxyribonuclease I (DNase I) activity is described. This method is based on the ability of PicoGreen dye to enhance its fluorescence...
4.
Urtti A, POLANSKY J, Lui G, Szoka F
J Drug Target
. 2000 Apr;
7(6):413-21.
PMID: 10758912
Non-viral gene therapy is a potential treatment to many incurable retinal diseases. To fulfill this promise, plasmid DNA must be delivered to the retinal target cells. We evaluated the efficacy...
5.
Tang M, Szoka F
Gene Ther
. 1997 Aug;
4(8):823-32.
PMID: 9338011
Four cationic polymers used to deliver DNA into cultured cells: polylysine, intact polyamidoamine dendrimer, fractured polyamidoamine dendrimer and polyethylenimine, are examined for their ability to interact with DNA. Complexes between...
6.
Hickman M, Malone R, Sih T, Knoell D, Szoka F, Walzem R, et al.
Hum Gene Ther
. 1994 Dec;
5(12):1477-83.
PMID: 7711140
The liver is an attractive target tissue for gene therapy. Current approaches for hepatic gene delivery include retroviral and adenoviral vectors, liposome/DNA, and peptide/DNA complexes. This study describes a technique...
7.
Chu C, Dijkstra J, Lai M, Hong K, Szoka F
Pharm Res
. 1990 Aug;
7(8):824-34.
PMID: 2172955
The intracellular processing of pH-sensitive liposomes composed of cholesterylhemisuccinate (CHEMS) and dioleoylphosphatidylethanolamine (DOPE) by eukaryotic cell lines has been compared to non-pH-sensitive liposomes made of CHEMS and dioleoylphosphatidylcholine (DOPC). The...
8.
Roe J, Szoka F, Verkman A
Analyst
. 1990 Apr;
115(4):353-8.
PMID: 2363517
A fluorescence fibre optic sensor has been developed for measurement of the potassium concentration in aqueous solution based on the change in optical absorbance of the hydrophobic indicator 7-decyl-2-methyl-4-(3',5'-dichlorophen-4'-one)indonaphth-1-o l...
9.
Roe J, Szoka F, Verkman A
Biophys Chem
. 1989 Jul;
33(3):295-302.
PMID: 2804247
An assay was developed for K+ in aqueous solution at neutral pH. The method was based on the change in optical absorbance of the hydrophobic indicator 7-(n-decyl)-2-methyl-4-(3',5'-dichlorophen-4'-one)indonaphthl++ +-1-ol (MEDPIN) in...
10.
Dijkstra J, Ryan J, Szoka F
J Immunol Methods
. 1988 Nov;
114(1-2):197-205.
PMID: 3263442
Previous studies on the mechanism of action of lipopolysaccharides (LPS) on macrophages have used wild-type lipopolysaccharide (wt-LPS) containing liposomes. In these studies the endotoxin was incorporated into liposomes by suspending...