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F C Holstege

Explore the profile of F C Holstege including associated specialties, affiliations and a list of published articles. Areas
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Articles 21
Citations 3153
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Recent Articles
1.
Snoeren N, Emmink B, Koerkamp M, van Hooff S, Goos J, van Houdt W, et al.
Br J Cancer . 2013 Sep; 109(6):1636-47. PMID: 24002600
Background: Little is known about the factors that drive metastasis formation in colorectal cancer (CRC). Here, we set out to identify genes and proteins in patients with colorectal liver metastases...
2.
Rao N, van Wolferen M, Gracanin A, Bhatti S, Krol M, Holstege F, et al.
J Physiol Pharmacol . 2009 Jul; 60 Suppl 1:73-84. PMID: 19609016
Spontaneous mammary tumors are the most prevalent type of neoplasms in women as well as in female dogs. Although ovarian hormones estrogen and progesterone are known to play a key...
3.
Brazma A, Hingamp P, Quackenbush J, Sherlock G, Spellman P, Stoeckert C, et al.
Nat Genet . 2001 Dec; 29(4):365-71. PMID: 11726920
Microarray analysis has become a widely used tool for the generation of gene expression data on a genomic scale. Although many significant results have been derived from microarray studies, one...
4.
Virbasius C, Holstege F, Young R, Green M
Curr Biol . 2001 Nov; 11(22):1794-8. PMID: 11719223
TFIIB is an RNA polymerase II general transcription factor (GTF) that has also been implicated in the mechanism of action of certain promoter-specific activators (see, for examples, [1-11]). TFIIB enters...
5.
Geisberg J, Holstege F, Young R, Struhl K
Mol Cell Biol . 2001 Apr; 21(8):2736-42. PMID: 11283253
NC2 (Dr1-Drap1 or Bur6-Ydr1) has been characterized in vitro as a general negative regulator of RNA polymerase II (Pol II) transcription that interacts with TATA-binding protein (TBP) and inhibits its...
6.
van Berkum N, Holstege F
Curr Opin Biotechnol . 2001 Feb; 12(1):48-52. PMID: 11167072
Expression profiling using DNA microarrays is starting to come of age. The past year has seen significant advances in the number, scope and quality of studies that incorporate expression profiling...
7.
Lee T, Causton H, Holstege F, Shen W, Hannett N, Jennings E, et al.
Nature . 2000 Jun; 405(6787):701-4. PMID: 10864329
The transcription factors TFIID and SAGA are multi-subunit complexes involved in transcription by RNA polymerase II. TFIID and SAGA contain common TATA-binding protein (TBP)-associated factor (TAF(II)) subunits and each complex...
8.
Wyrick J, Holstege F, Jennings E, Causton H, Shore D, Grunstein M, et al.
Nature . 1999 Dec; 402(6760):418-21. PMID: 10586882
Eukaryotic genomes are packaged into nucleosomes, which are thought to repress gene expression generally. Repression is particularly evident at yeast telomeres, where genes within the telomeric heterochromatin appear to be...
9.
Kobor M, Archambault J, Lester W, Holstege F, Gileadi O, Jansma D, et al.
Mol Cell . 1999 Aug; 4(1):55-62. PMID: 10445027
The carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II is phosphorylated soon after transcriptional initiation. We show here that the essential FCP1 gene of S. cerevisiae is...
10.
Holstege F, Young R
Proc Natl Acad Sci U S A . 1999 Jan; 96(1):2-4. PMID: 9874759
No abstract available.