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F C Campbell

Explore the profile of F C Campbell including associated specialties, affiliations and a list of published articles. Areas
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Articles 71
Citations 818
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Recent Articles
1.
Jagan I, Fatehullah A, Deevi R, Bingham V, Campbell F
Oncogene . 2012 May; 32(10):1305-15. PMID: 22543585
Disruption of glandular architecture associates with poor clinical outcome in high-grade colorectal cancer (CRC). Phosphatase and tensin homolog deleted on chromosome ten (PTEN) regulates morphogenic growth of benign MDCK (Madin...
2.
Deevi R, Fatehullah A, Jagan I, Nagaraju M, Bingham V, Campbell F
Br J Cancer . 2011 Sep; 105(9):1313-21. PMID: 21952626
Background: Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) regulation of the Rho-like GTPase Cdc42 has a central role in epithelial polarised growth, but effects of this molecular network...
3.
Stevenson R, Fatehullah A, Jagan I, Deevi R, Bingham V, Irvine A, et al.
Clin Exp Immunol . 2011 Mar; 164(2):202-10. PMID: 21361912
Identification of immune modifiers of inherited cancer syndromes may provide a rationale for preventive therapy. Cowden disease (CD) is a genetically heterogeneous inherited cancer syndrome that arises predominantly from germline...
4.
Mole D, ONeill C, Hamilton P, Olabi B, Robinson V, Williams L, et al.
Br J Cancer . 2011 Feb; 104(6):1007-12. PMID: 21343932
Background: A transcription regulatory complex (TRC) that includes Ets1, Ets2, PEA3 and β-catenin/T-cell factors regulates osteopontin (OPN) that is implicated in colorectal cancer (CRC) dissemination. The consistency of OPN transcriptional...
5.
El-Tanani M, Jin D, Campbell F, Johnston P
Oncogene . 2009 Nov; 29(5):752-62. PMID: 19901966
Osteopontin is a secreted, integrin-binding and phosphorylated acidic glycoprotein, which has an important role in tumour progression. We have shown that Wnt, Ets, AP-1, c-jun and beta-catenin/Lef-1/Tcf-1 stimulates OPN transcription...
6.
Campbell F, Xu H, El-Tanani M, Crowe P, Bingham V
Biochem Pharmacol . 2009 Sep; 79(1):1-9. PMID: 19737544
Substantive evidence implicates vitamin D receptor (VDR) or its natural ligand 1alpha,25-(OH)2 D3 in modulation of tumor growth. However, both human and animal studies indicate tissue-specificity of effect. Epidemiological studies...
7.
Campbell F, Maxwell R
Surgeon . 2009 May; 7(2):96-100. PMID: 19408802
Colorectal cancer (CRC) is the most feared long-term complication in patients with ulcerative colitis (UC) and Crohn's colitis. Surveillance by colonoscopy and serial biopsy is conducted to identify patients most...
8.
Kurisetty V, Johnston P, Johnston N, Erwin P, Crowe P, Fernig D, et al.
Oncogene . 2008 Sep; 27(57):7139-49. PMID: 18794800
Osteopontin (OPN) is a phosphorylated glycoprotein that binds to alpha v-containing integrins and is important in malignant transformation and cancer. Previously, we have utilized suppressive subtractive hybridization between mRNAs isolated...
9.
Solomon L, Vogiatzis I, Craig E, Campbell F
Ulster Med J . 2005 Oct; 74(2):134-5. PMID: 16235769
No abstract available.
10.
Donnelly E, Bardwell H, Thomas G, Williams E, Hoper M, Crowe P, et al.
Br J Cancer . 2005 Jun; 92(12):2160-5. PMID: 15928667
Metallothionein (MT) crypt-restricted immunopositivity indices (MTCRII) are colonic crypt stem cell mutation markers that may be induced early and in abundance after mutagen treatment. Metallothionein is the endogenous reporter gene...