Ezequiel Calvo-Roitberg
Overview
Explore the profile of Ezequiel Calvo-Roitberg including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
15
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Recent Articles
1.
Calvo-Roitberg E, Daniels R, Pai A
Genome Res
. 2024 Nov;
34(11):1719-1734.
PMID: 39567236
Long-read sequencing (LRS) technologies have the potential to revolutionize scientific discoveries in RNA biology through the comprehensive identification and quantification of full-length mRNA isoforms. Despite great promise, challenges remain in...
2.
Calvo-Roitberg E, Carroll C, Venev S, Kim G, Mick S, Dekker J, et al.
bioRxiv
. 2024 Jan;
PMID: 38260419
The expression of a precise mRNA transcriptome is crucial for establishing cell identity and function, with dozens of alternative isoforms produced for a single gene sequence. The regulation of mRNA...
3.
Torres-Ulloa L, Calvo-Roitberg E, Pai A
RNA
. 2024 Jan;
30(3):256-270.
PMID: 38164598
Cleavage and polyadenylation is necessary for the formation of mature mRNA molecules. The rate at which this process occurs can determine the temporal availability of mRNA for subsequent function throughout...
4.
Calvo-Roitberg E, Daniels R, Pai A
bioRxiv
. 2023 Aug;
PMID: 37546743
Long-read sequencing (LRS) technologies have the potential to revolutionize scientific discoveries in RNA biology, especially by enabling the comprehensive identification and quantification of full length mRNA isoforms. However, inherently high...
5.
Wang F, Calvo-Roitberg E, Rembetsy-Brown J, Fang M, Sousa J, Kartje Z, et al.
Nucleic Acids Res
. 2022 Dec;
50(22):12657-12673.
PMID: 36511872
Friedreich's ataxia is an incurable disease caused by frataxin (FXN) protein deficiency, which is mostly induced by GAA repeat expansion in intron 1 of the FXN gene. Here, we identified...
6.
MacMillan H, Kong Y, Calvo-Roitberg E, Alonso L, Pai A
Sci Rep
. 2022 May;
12(1):7745.
PMID: 35546161
The antisense non-coding RNA in the INK locus (ANRIL) is a hotspot for genetic variants associated with cardiometabolic disease. We recently found increased ANRIL abundance in human pancreatic islets from...
7.
Fiszbein A, McGurk M, Calvo-Roitberg E, Kim G, Burge C, Pai A
Sci Adv
. 2022 Jan;
8(3):eabk1752.
PMID: 35044812
Messenger RNA isoform differences are predominantly driven by alternative first, internal, and last exons. Despite the importance of classifying exons to understand isoform structure, few tools examine isoform-specific exon usage....