Ewan D Booth
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Explore the profile of Ewan D Booth including associated specialties, affiliations and a list of published articles.
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14
Citations
223
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Recent Articles
1.
Fowler P, Bearzatto A, Beevers C, Booth E, Donner E, Gan L, et al.
Mutagenesis
. 2024 Jan;
39(2):146-155.
PMID: 38183270
The two-test in vitro battery for genotoxicity testing (Ames and micronucleus) has in the majority of cases replaced the three-test battery (as two-test plus mammalian cell gene mutation assay) for...
2.
Hasselgren C, Ahlberg E, Akahori Y, Amberg A, Anger L, Atienzar F, et al.
Regul Toxicol Pharmacol
. 2019 Jun;
107:104403.
PMID: 31195068
In silico toxicology (IST) approaches to rapidly assess chemical hazard, and usage of such methods is increasing in all applications but especially for regulatory submissions, such as for assessing chemicals...
3.
Myatt G, Ahlberg E, Akahori Y, Allen D, Amberg A, Anger L, et al.
Regul Toxicol Pharmacol
. 2018 Apr;
96:1-17.
PMID: 29678766
The present publication surveys several applications of in silico (i.e., computational) toxicology approaches across different industries and institutions. It highlights the need to develop standardized protocols when conducting toxicity-related predictions....
4.
Booth E, Rawlinson P, Maria Fagundes P, Leiner K
Environ Mol Mutagen
. 2017 Mar;
58(5):325-344.
PMID: 28329407
Active ingredients in plant protection products are subject to rigorous safety assessment during their development, including assessment of genotoxicity. Plant protection products are used for agriculture in multiple regions and...
5.
Hand L, Richardson K, Hadfield S, Whalley S, Rawlinson P, Booth E
Regul Toxicol Pharmacol
. 2016 Nov;
83:109-116.
PMID: 27871869
This paper describes the further development of a read-across approach applicable to the toxicological assessment of structurally-related xenobiotic metabolites. The approach, which can be applied in the absence of definitive...
6.
Ball N, Cronin M, Shen J, Blackburn K, Booth E, Bouhifd M, et al.
ALTEX
. 2016 Feb;
33(2):149-66.
PMID: 26863606
Grouping of substances and utilizing read-across of data within those groups represents an important data gap filling technique for chemical safety assessments. Categories/analogue groups are typically developed based on structural...
7.
Patlewicz G, Ball N, Becker R, Booth E, Cronin M, Kroese D, et al.
ALTEX
. 2014 Nov;
31(4):387-96.
PMID: 25368965
Read-across is a data gap filling technique used within category and analogue approaches. It has been utilized as an alternative approach to address information requirements under various past and present...
8.
Patlewicz G, Ball N, Booth E, Hulzebos E, Zvinavashe E, Hennes C
Regul Toxicol Pharmacol
. 2013 Jun;
67(1):1-12.
PMID: 23764304
Read-across has generated much attention since it may be used as an alternative approach for addressing the information requirements under regulatory programmes, notably the EU's REACH regulation. Read-across approaches are...
9.
Shane B, Zeiger E, Piegorsch W, Booth E, Goodman J, Peffer R
Environ Mol Mutagen
. 2012 Feb;
53(1):1-9.
PMID: 22329022
Propiconazole (PPZ) is a conazole fungicide that is not mutagenic, clastogenic, or DNA damaging in standard in vitro and in vivo genetic toxicity tests for gene mutations, chromosome aberrations, DNA...
10.
Booth E, Jones E, Elliott B
Regul Toxicol Pharmacol
. 2007 Oct;
49(3):316-26.
PMID: 17936460
Dichlorvos has been in widespread use as an insecticide for over 40 years, during which time its carcinogenicity and genotoxicity have been evaluated extensively. In vitro genotoxicity assays--have shown dichlorvos...