Ewa Grela
Overview
Explore the profile of Ewa Grela including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
242
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Recent Articles
1.
Janik S, Luchowski R, Grela E, Grudzinski W, Gruszecki W
J Phys Chem Lett
. 2024 Apr;
15(18):4823-4827.
PMID: 38668706
Amphotericin B is a popular antifungal antibiotic, but the exact way it works is still a matter of debate. Here, we used monolayers composed of phosphatidylcholine with ergosterol as a...
2.
Janik S, Grela E, Staczek S, Zdybicka-Barabas A, Luchowski R, Gruszecki W, et al.
Molecules
. 2023 Jun;
28(12).
PMID: 37375242
Amphotericin B is a popular antifungal antibiotic, and despite decades of pharmacological application, the exact mode of its biological activity is still a matter of debate. Amphotericin B-silver hybrid nanoparticles...
3.
Grela E, Staczek S, Nowak M, Pawlikowska-Pawlega B, Zdybicka-Barabas A, Janik S, et al.
J Phys Chem B
. 2023 Apr;
127(16):3632-3640.
PMID: 37071547
Amphotericin B (AmB) is a life-saving and widely used antifungal antibiotic, but its therapeutic applicability is limited due to severe side effects. Here, we report that the formulation of the...
4.
Maciejczyk A, Kapral-Piotrowska J, Sumorek-Wiadro J, Zajac A, Grela E, Luchowski R, et al.
Cancers (Basel)
. 2021 Jun;
13(11).
PMID: 34072003
Aim: The anti-glioma effect of lensoside Aβ alone and in combination with sorafenib (pro-survival Raf kinase inhibitor) was evaluated for the first time in terms of programmed cell death induction...
5.
Zielinska J, Wieczor M, Chodnicki P, Grela E, Luchowski R, Nierzwicki L, et al.
Nanoscale
. 2021 Feb;
13(6):3686-3697.
PMID: 33543744
Amphotericin B (AmB), one of the most powerful but also toxic drugs used to treat systemic mycoses, is believed to selectively permeabilize fungal cell membranes to ions in a sterol-dependent...
6.
Grela E, Zdybicka-Barabas A, Pawlikowska-Pawlega B, Cytrynska M, Wlodarczyk M, Grudzinski W, et al.
Sci Rep
. 2019 Nov;
9(1):17029.
PMID: 31745151
Amphotericin B is an antibiotic used as the "gold standard" in the treatment of life-threatening fungal infections. Several molecular mechanisms have been proposed to explain exceptionally high effectiveness of amphotericin...
7.
Kozlowska J, Grela E, Baczynska D, Grabowiecka A, Aniol M
Molecules
. 2019 Feb;
24(4).
PMID: 30769816
In our investigation, we concentrated on naringenin ()-a widely studied flavanone that occurs in citrus fruits. As a result of a reaction with a range of alkyl iodides, 7 novel...
8.
Koziol A, Grela E, Macegoniuk K, Grabowiecka A, Lochynski S
Nat Prod Res
. 2019 Jan;
34(8):1074-1079.
PMID: 30663357
Incorporation of the Beckmann rearrangement into the presented research resulted in the formation of nitrogen-containing terpenoid derivatives originating from naturally occurring compounds. Both starting monoterpenes and obtained derivatives were subjected...
9.
Koziol A, Jasnowski M, Grela E, Szczepanik M, Gabrys B, Dancewicz K, et al.
Chem Biodivers
. 2019 Jan;
16(2):e1800411.
PMID: 30656843
In the synthesis performed in this study, derivatives of 4-tert-butylcyclohexanone 1 were obtained using typical reactions of organic synthesis. The bioactivity of the selected compounds was evaluated. 1-(Bromomethyl)-8-tert-butyl-2-oxaspiro[4.5]decan-3-one (5) was...
10.
Koziol A, Fratczak J, Grela E, Szczepanik M, Gabrys B, Dancewicz K, et al.
Nat Prod Res
. 2018 Nov;
34(10):1399-1403.
PMID: 30427737
Terpenoid derivatives, which contain a preserved carane system in their structure, exhibit a broad spectrum of biological activities. Among them, we can distinguish insecticides, structures with pharmacological application etc. In...