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Everett H Chen

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Articles 6
Citations 277
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Recent Articles
1.
Singh K, Lezama L, Kurzer J, Oak J, Schultz L, Walkush A, et al.
Am J Surg Pathol . 2022 Aug; 47(1):81-90. PMID: 36001451
Classic Hodgkin lymphoma (CHL) patients may infrequently present with a prior or recurrent disease with discordant histology resembling non-Hodgkin lymphomas. These include primary mediastinal large B-cell lymphoma (PMBL), diffuse large...
2.
Goldberg S, Redman M, Lilenbaum R, Politi K, Stinchcombe T, Horn L, et al.
J Clin Oncol . 2020 Oct; 38(34):4076-4085. PMID: 33021871
Purpose: The irreversible ErbB family tyrosine kinase inhibitor (TKI) afatinib plus the EGFR monoclonal antibody cetuximab was previously shown to overcome resistance to EGFR TKIs. We studied whether the combination...
3.
Ayton P, Chen E, Cleary M
Mol Cell Biol . 2004 Nov; 24(23):10470-8. PMID: 15542854
The MLL gene is a frequent target for leukemia-associated chromosomal translocations that generate dominant-acting chimeric oncoproteins. These invariably contain the amino-terminal 1,400 residues of MLL fused with one of a...
4.
So C, Lin M, Ayton P, Chen E, Cleary M
Cancer Cell . 2003 Sep; 4(2):99-110. PMID: 12957285
MLL is a histone methyltransferase that can be converted into an oncoprotein by acquisition of transcriptional effector domains following heterologous protein fusions with a variety of nuclear transcription factors, cofactors,...
5.
Nie Z, Yan Z, Chen E, Sechi S, Ling C, Zhou S, et al.
Mol Cell Biol . 2003 Apr; 23(8):2942-52. PMID: 12665591
The SWI/SNF family of chromatin-remodeling complexes has been discovered in many species and has been shown to regulate gene expression by assisting transcriptional machinery to gain access to their sites...
6.
DiMartino J, Ayton P, Chen E, Naftzger C, Young B, Cleary M
Blood . 2002 May; 99(10):3780-5. PMID: 11986236
The t(10;11)(p12;q23) chromosomal translocation in human acute myeloid leukemia results in the fusion of the MLL and AF10 genes. The latter codes for a novel leucine zipper protein, one of...