Evelyn Tiffany-Castiglioni
Overview
Explore the profile of Evelyn Tiffany-Castiglioni including associated specialties, affiliations and a list of published articles.
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31
Citations
418
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Recent Articles
1.
Gao F, Wang X, Li Z, Zhou A, Tiffany-Castiglioni E, Xie L, et al.
Oncol Lett
. 2017 Jul;
14(1):15-22.
PMID: 28693129
Secretion of granular glands from the skin of amphibians is a fascinating resource of active substances, particularly for cancer therapy in clinical practice of Traditional Chinese Medicine. A variety of...
2.
Moreno J, Tiffany-Castiglioni E
Neurochem Res
. 2014 Aug;
40(2):329-35.
PMID: 25107299
Chaperones are essential for the proper folding of proteins, and their dysfunction or depletion may be a key factor in protein folding disorders in the central nervous system. In normal...
3.
Qian Y, Meng B, Zhang X, Zheng Y, Taylor R, Tiffany-Castiglioni E
Neurochem Res
. 2012 Nov;
38(2):321-9.
PMID: 23161089
Our previous study indicated that Hspa5 directly interacts with copper (Cu) to maintain Cu homeostasis in astrocytes. In this study, we explored the possibility that Cu forms a specific complex...
4.
Tiffany-Castiglioni E, Qian Y
Neurotoxicology
. 2012 Feb;
33(3):545-57.
PMID: 22370090
Chaperones in the endoplasmic reticulum play vital roles in the folding, assembly, and post-translational modification of secretory proteins and also recycle, refold, or initiate degradation of misfolded proteins. Chaperone deficiencies...
5.
Qian Y, Zheng Y, Taylor R, Tiffany-Castiglioni E
Brain Res
. 2012 Feb;
1447:9-19.
PMID: 22342161
Copper (Cu) ion availability in tissues and cells must be closely regulated within safe limits by Cu transporters and chaperones. Astrocytes play key roles in metal homeostasis and distribution in...
6.
Tiffany-Castiglioni E, Hong S, Qian Y
Int J Dev Neurosci
. 2011 Oct;
29(8):811-8.
PMID: 21968186
Copper (Cu) is an essential trace element in the brain that can be toxic at elevated levels. Cu accumulation is a suspected etiology in several neurodegenerative diseases, including Alzheimer's disease,...
7.
Tiffany-Castiglioni E, Qian Y, Barhoumi R, Zheng Y
Methods Mol Biol
. 2011 Aug;
758:29-48.
PMID: 21815057
Molecular chaperones assist the folding of nascent proteins during translation into their correct conformations. Neurotoxic metals such as copper (Cu) and lead (Pb) may produce a deficiency in chaperone function...
8.
Donnelly K, Lingenfelter R, Cizmas L, Falahatpisheh M, Qian Y, Tang Y, et al.
Environ Toxicol Pharmacol
. 2011 Jul;
18(2):135-41.
PMID: 21782742
One of the initial steps in remediating contaminated environments is to assess the human and ecological health risk associated with exposure to contaminants in a specific medium. Presented here are...
9.
Watanabe K, Andersen M, Basu N, Carvan 3rd M, Crofton K, King K, et al.
Environ Toxicol Chem
. 2010 Oct;
30(1):9-21.
PMID: 20963854
An adverse outcome pathway (AOP) is a sequence of key events from a molecular-level initiating event and an ensuing cascade of steps to an adverse outcome with population-level significance. To...
10.
Yang W, Tiffany-Castiglioni E, Lee M, Son I
Toxicol Lett
. 2010 Sep;
199(3):239-46.
PMID: 20851755
Paraquat produces dopaminergic pathologies of Parkinson's disease, in which cyclooxygenase-2 (COX-2) is implicated. However, it is unclear whether paraquat induces toxicity within dopaminergic neurons through COX-2. To address this, human...