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Evelien Mets

Explore the profile of Evelien Mets including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 359
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Recent Articles
1.
Van Peer G, Mets E, Claeys S, De Punt I, Lefever S, Ongenaert M, et al.
PLoS One . 2018 Mar; 13(3):e0194017. PMID: 29522551
Introduction: Despite the established contribution of deregulated microRNA (miRNA) function to carcinogenesis, relatively few miRNA-cancer gene interactions have been validated, making it difficult to appreciate the true complexity of miRNA-cancer...
2.
Beckers A, Van Peer G, Carter D, Mets E, Althoff K, Cheung B, et al.
Oncotarget . 2014 Oct; 6(7):5204-16. PMID: 25294817
MYCN is a transcription factor that plays key roles in both normal development and cancer. In neuroblastoma, MYCN acts as a major oncogenic driver through pleiotropic effects regulated by multiple...
3.
Mets E, Van Peer G, Van der Meulen J, Boice M, Taghon T, Goossens S, et al.
Haematologica . 2014 Jun; 99(8):1326-33. PMID: 24895337
T-cell acute lymphoblastic leukemia arises from the leukemic transformation of developing thymocytes and results from cooperative genetic lesions. Inactivation of the PHF6 gene is frequently observed in T-cell acute lymphoblastic...
4.
Bustin S, Benes V, Garson J, Hellemans J, Huggett J, Kubista M, et al.
Nat Methods . 2013 Nov; 10(11):1063-7. PMID: 24173381
Two surveys of over 1,700 publications whose authors use quantitative real-time PCR (qPCR) reveal a lack of transparent and comprehensive reporting of essential technical information. Reporting standards are significantly improved...
5.
Rihani A, Van Maerken T, Pattyn F, Van Peer G, Beckers A, De Brouwer S, et al.
PLoS One . 2013 Aug; 8(8):e71776. PMID: 23977142
Background: Measuring messenger RNA (mRNA) levels using the reverse transcription quantitative polymerase chain reaction (RT-qPCR) is common practice in many laboratories. A specific set of mRNAs as internal control reference...
6.
Mavrakis K, Van der Meulen J, Wolfe A, Liu X, Mets E, Taghon T, et al.
Nat Genet . 2011 Jun; 43(7):673-8. PMID: 21642990
The importance of individual microRNAs (miRNAs) has been established in specific cancers. However, a comprehensive analysis of the contribution of miRNAs to the pathogenesis of any specific cancer is lacking....