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Evan D Paul

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Articles 21
Citations 631
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Recent Articles
1.
Boehm K, El Nahhas O, Marra A, Waters M, Jee J, Braunstein L, et al.
Nat Commun . 2025 Mar; 16(1):2106. PMID: 40025017
The Oncotype DX® Recurrence Score (RS) is an assay for hormone receptor-positive early breast cancer with extensively validated predictive and prognostic value. However, its cost and lag time have limited...
2.
Paul E, Huraiova B, Valkova N, Matyasovska N, Gabrisova D, Gubova S, et al.
Nat Commun . 2025 Jan; 16(1):226. PMID: 39747865
Current assays fail to address breast cancer's complex biology and accurately predict treatment response. On a retrospective cohort of 1082 female breast tissues, we develop and validate mFISHseq, which integrates...
3.
Paul E, Huraiova B, Valkova N, Birknerova N, Gabrisova D, Gubova S, et al.
medRxiv . 2023 Dec; PMID: 38105959
On a retrospective cohort of 1,082 FFPE breast tumors, we demonstrated the analytical validity of a test using multiplexed RNA-FISH-guided laser capture microdissection (LCM) coupled with RNA-sequencing (mFISHseq), which showed...
4.
Szobi A, Buranovska K, Vojtassakova N, Lovisek D, Ozbasak H, Szeibeczederova S, et al.
Commun Biol . 2023 Mar; 6(1):233. PMID: 36864129
Sensitive and rapid point-of-care assays have been crucial in the global response to SARS-CoV-2. Loop-mediated isothermal amplification (LAMP) has emerged as an important diagnostic tool given its simplicity and minimal...
5.
Radvanszka M, Paul E, Hajdu R, Borsova K, Kovacova V, Putaj P, et al.
Microb Biotechnol . 2022 Mar; 15(7):1995-2021. PMID: 35316574
Sensitive and accurate RT-qPCR tests are the primary diagnostic tools to identify SARS-CoV-2-infected patients. While many SARS-CoV-2 RT-qPCR tests are available, there are significant differences in test sensitivity, workflow (e.g....
6.
Borsova K, Paul E, Kovacova V, Radvanszka M, Hajdu R, cabanova V, et al.
Sci Rep . 2021 Oct; 11(1):20494. PMID: 34650153
The emergence of a novel SARS-CoV-2 B.1.1.7 variant sparked global alarm due to increased transmissibility, mortality, and uncertainty about vaccine efficacy, thus accelerating efforts to detect and track the variant....
7.
Brejova B, Borsova K, Hodorova V, cabanova V, Reizigova L, Paul E, et al.
Virus Genes . 2021 Aug; 57(6):556-560. PMID: 34448987
SARS-CoV-2 mutants carrying the ∆H69/∆V70 deletion in the amino-terminal domain of the Spike protein emerged independently in at least six lineages of the virus (namely, B.1.1.7, B.1.1.298, B.1.160, B.1.177, B.1.258,...
8.
Hale M, Lukkes J, Dady K, Kelly K, Paul E, Smith D, et al.
Behav Brain Res . 2018 Nov; 359:428-439. PMID: 30468787
Evidence suggests that affective disorders are associated with altered thermoregulation, and it has been hypothesized that therapeutic strategies targeting body-to-brain thermosensory systems may be effective for treating depression. Consistent with...
9.
Hale M, Lukkes J, Dady K, Kelly K, Paul E, Smith D, et al.
Prog Neuropsychopharmacol Biol Psychiatry . 2017 Jun; 79(Pt B):162-168. PMID: 28619470
Background: Open and randomized, double blind, placebo-controlled clinical trials have demonstrated clinical efficacy of infrared whole-body hyperthermia in treatment of major depressive disorder (MDD). Demonstration of antidepressant-like behavioral effects of...
10.
Stamper C, Hennessey P, Hale M, Lukkes J, Donner N, Lowe K, et al.
Stress . 2015 Jan; 18(1):76-87. PMID: 25556980
Previous studies suggest that multiple corticolimbic and hypothalamic structures are involved in glucocorticoid-mediated feedback inhibition of the hypothalamic-pituitary-adrenal (HPA) axis, including the dorsomedial hypothalamus (DMH), but a potential role of...