Eva Saghy
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Explore the profile of Eva Saghy including associated specialties, affiliations and a list of published articles.
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20
Citations
307
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Recent Articles
1.
Voros I, Onodi Z, Toth V, Gergely T, Saghy E, Gorbe A, et al.
Biomedicines
. 2022 Jul;
10(7).
PMID: 35884882
Dipeptidyl-peptidase-4 (DPP4) inhibitors are novel medicines for diabetes. The SAVOR-TIMI-53 clinical trial revealed increased heart-failure-associated hospitalization in saxagliptin-treated patients. Although this side effect could limit therapeutic use, the mechanism of...
2.
Szabo D, Sarszegi Z, Polgar B, Saghy E, Reglodi D, Toth T, et al.
Int J Mol Sci
. 2022 Apr;
23(7).
PMID: 35409075
Pituitary adenylate cyclase activating polypeptide-38 (PACAP-38) is a multifunctional neuropeptide, which may play a role in cardioprotection. However, little is known about the presence of PACAP-38 in heart failure (HF)...
3.
Voros I, Saghy E, Pohoczky K, Makkos A, Onodi Z, Brenner G, et al.
Front Pharmacol
. 2021 Nov;
12:663655.
PMID: 34803662
Little is known about the role of the neuropeptide somatostatin (SST) in myocardial ischemia/reperfusion injury and cardioprotection. Here, we investigated the direct cardiocytoprotective effect of SST on ischemia/reperfusion injury in...
4.
Szabo D, Sarszegi Z, Polgar B, Saghy E, Nemeth A, Reglodi D, et al.
Int J Mol Sci
. 2021 Apr;
22(6).
PMID: 33809145
Acute myocardial infarction (MI) is one of the most common causes of death worldwide. Pituitary adenylate cyclase activating polypeptide (PACAP) is a cardioprotective neuropeptide expressing its receptors in the cardiovascular...
5.
Horvath A, Payrits M, Steib A, Kantas B, Biro-Sut T, Erostyak J, et al.
Front Pharmacol
. 2021 Feb;
11:593319.
PMID: 33584270
Transient Receptor Potential (TRP) Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons, and integratively regulate nociceptor and inflammatory functions. Lipid rafts are...
6.
Tekus V, Horvath A, Cseko K, Szabadfi K, Kovacs-Valasek A, Danyadi B, et al.
Biomed Pharmacother
. 2020 Dec;
134:111105.
PMID: 33338750
Diabetes mellitus is a common metabolic disease leading to hyperglycemia due to insufficient pancreatic insulin production or effect. Amine oxidase copper containing 3 (AOC3) is an enzyme that belongs to...
7.
Payrits M, Horvath A, Biro-Suto T, Erostyak J, Makkai G, Saghy E, et al.
Int J Mol Sci
. 2020 Jul;
21(14).
PMID: 32708653
Transient Receptor Potential Vanilloid 1 and Ankyrin 1 (TRPV1, TRPA1) cation channels are expressed in nociceptive primary sensory neurons and regulate nociceptor and inflammatory functions. Resolvins are endogenous lipid mediators....
8.
Schreckenberg R, Klein J, Kutsche H, Schulz R, Gomori K, Bencsik P, et al.
J Cell Mol Med
. 2020 Apr;
24(10):5528-5541.
PMID: 32297702
Ischaemic post-conditioning (IPoC) is a clinical applicable procedure to reduce reperfusion injury. Non-responsiveness to IPoC possibly caused by co-morbidities limits its clinical attractiveness. We analysed differences in the expression of...
9.
Saghy E, Voros I, Agg B, Kiss B, Koncsos G, Varga Z, et al.
Int J Mol Sci
. 2020 Apr;
21(6).
PMID: 32244869
Little is known about the mechanism of prediabetes-induced cardiac dysfunction. Therefore, we aimed to explore key molecular changes with transcriptomic and bioinformatics approaches in a prediabetes model showing heart failure...
10.
Brenner G, Makkos A, Nagy C, Onodi Z, Sayour N, Gergely T, et al.
Cells
. 2020 Mar;
9(3).
PMID: 32111102
Cardiac adverse effects are among the leading causes of the discontinuation of clinical trials and the withdrawal of drugs from the market. The novel concept of 'hidden cardiotoxicity' is defined...