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Eva Martinez-Pinilla

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Recent Articles
1.
Menendez-Perez C, Rivas-Santisteban R, Del Valle E, Tolivia J, Navarro A, Franco R, et al.
Int J Mol Sci . 2024 Apr; 25(8). PMID: 38673761
Multiple sclerosis (MS) is an autoimmune, inflammatory, and neurodegenerative disease of the central nervous system for which there is no cure, making it necessary to search for new treatments. The...
2.
Junceda S, Cruz-Alonso M, Fernandez B, Pereiro R, Martinez-Pinilla E, Navarro A
Biomolecules . 2024 Mar; 14(3). PMID: 38540715
Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by cognitive decline and neuropathological hallmarks, including β-amyloid (Aβ) plaques, Tau tangles, synaptic dysfunction and neurodegeneration. Emerging evidence suggests that abnormal...
3.
Del Valle E, Rubio-Sardon N, Menendez-Perez C, Martinez-Pinilla E, Navarro A
Int J Mol Sci . 2023 Nov; 24(21). PMID: 37958618
Neuropsychiatric disorders (NDs) are a diverse group of pathologies, including schizophrenia or bipolar disorders, that directly affect the mental and physical health of those who suffer from them, with an...
4.
Franco R, Navarro G, Martinez-Pinilla E
Int Rev Neurobiol . 2023 Sep; 170:49-71. PMID: 37741696
Adenosine is a neuroregulatory nucleoside that acts through four G protein-coupled receptors (GPCRs), A, A, A and A, which are widely expressed in cells of the nervous system. The A...
5.
Franco R, Martinez-Pinilla E
BMC Psychiatry . 2023 Jun; 23(1):411. PMID: 37286934
Theobromine is an abundant methylxanthine in cocoa/chocolate. A recent article in BMC Psychiatry concludes that theobromine consumption increases the risk of depression. In our opinion, it is difficult to make...
6.
Lillo J, Garcia-Perez I, Lillo A, Serrano-Marin J, Martinez-Pinilla E, Navarro G, et al.
Front Pharmacol . 2023 Jun; 14:1108617. PMID: 37266149
Heteromer formation is unknown for the olfactory family of G protein-coupled receptors (GPCRs). We here identified, in a heterologous system, heteromers formed by the adenosine A receptor (AR), which is...
7.
Zamarbide M, Martinez-Pinilla E, Gil-Bea F, Yanagisawa M, Franco R, Perez-Mediavilla A
Int J Mol Sci . 2022 Apr; 23(7). PMID: 35408893
The free fatty acid FFA3 receptor (FFA3R) belongs to the superfamily of G-protein-coupled receptors (GPCRs). In the intestine and adipose tissue, it is involved in the regulation of energy metabolism,...
8.
Franco R, Casanovas B, Camps J, Navarro G, Martinez-Pinilla E
Curr Issues Mol Biol . 2021 Jul; 43(2):650-664. PMID: 34287292
Although antioxidants can act locally to react with an oxidant, oral administration of "antioxidants" is quite useless in treating oxidative stress in tissues. Furthermore, it does not make sense to...
9.
Martinez-Pinilla E, Rubio-Sardon N, Villar-Conde S, Navarro G, Del Valle E, Tolivia J, et al.
Brain Sci . 2021 Mar; 11(2). PMID: 33671675
Suitable in vivo and in vitro models are instrumental for the development of new drugs aimed at improving symptoms or progression of multiple sclerosis (MS). The cuprizone (CPZ)-induced murine model...
10.
Martinez-Pinilla E, Rubio-Sardon N, Pelaez R, Garcia-Alvarez E, Del Valle E, Tolivia J, et al.
Int J Mol Sci . 2021 Jan; 22(3). PMID: 33514021
Apolipoprotein D (Apo D) overexpression is a general finding across neurodegenerative conditions so the role of this apolipoprotein in various neuropathologies such as multiple sclerosis (MS) has aroused a great...