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Eva Martinez-Garcia

Explore the profile of Eva Martinez-Garcia including associated specialties, affiliations and a list of published articles. Areas
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Articles 9
Citations 1085
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Recent Articles
1.
Perez N, Accuosto P, Bravo A, Cuadros M, Martinez-Garcia E, Saggion H, et al.
Bioinformatics . 2019 Nov; 36(6):1872-1880. PMID: 31730202
Motivation: Biomedical literature is one of the most relevant sources of information for knowledge mining in the field of Bioinformatics. In spite of English being the most widely addressed language...
2.
Popovic R, Martinez-Garcia E, Giannopoulou E, Zhang Q, Zhang Q, Ezponda T, et al.
PLoS Genet . 2014 Sep; 10(9):e1004566. PMID: 25188243
Overexpression of the histone methyltransferase MMSET in t(4;14)+ multiple myeloma patients is believed to be the driving factor in the pathogenesis of this subtype of myeloma. MMSET catalyzes dimethylation of...
3.
Sullivan L, Martinez-Garcia E, Nguyen H, Mullen A, Dufour E, Sudarshan S, et al.
Mol Cell . 2013 Jun; 51(2):236-48. PMID: 23747014
The tricarboxylic acid cycle enzyme fumarate hydratase (FH) has been identified as a tumor suppressor in a subset of human renal cell carcinomas. Human FH-deficient cancer cells display high fumarate...
4.
Beguelin W, Popovic R, Teater M, Jiang Y, Bunting K, Rosen M, et al.
Cancer Cell . 2013 May; 23(5):677-92. PMID: 23680150
The EZH2 histone methyltransferase is highly expressed in germinal center (GC) B cells and targeted by somatic mutations in B cell lymphomas. Here, we find that EZH2 deletion or pharmacologic...
5.
Zheng Y, Sweet S, Popovic R, Martinez-Garcia E, Tipton J, Thomas P, et al.
Proc Natl Acad Sci U S A . 2012 Aug; 109(34):13549-54. PMID: 22869745
We have developed a targeted method to quantify all combinations of methylation on an H3 peptide containing lysines 27 and 36 (H3K27-K36). By using stable isotopes that separately label the...
6.
Martinez-Garcia E, Popovic R, Min D, Sweet S, Thomas P, Zamdborg L, et al.
Blood . 2010 Oct; 117(1):211-20. PMID: 20974671
The multiple myeloma SET domain (MMSET) protein is overexpressed in multiple myeloma (MM) patients with the translocation t(4;14). Although studies have shown the involvement of MMSET/Wolf-Hirschhorn syndrome candidate 1 in...
7.
Martinez-Garcia E, Irigoyen M, Gonzalez-Moreno O, Corrales L, Teijeira A, Salvo E, et al.
Toxicol Sci . 2010 May; 116(2):467-76. PMID: 20457658
Cigarette smoking is strongly correlated with the onset of lung cancer. Nicotine, a major component in cigarette smoke, has been found to promote tumor growth and angiogenesis, as well as...
8.
Martinez-Garcia E, Licht J
Nat Genet . 2010 Jan; 42(2):100-1. PMID: 20104248
A new study now reports recurrent somatic mutation of EZH2, a histone methyltransferase that modifies H3K27, in diffuse large B-cell lymphoma (DLBCL). There is now evidence for both increased and...
9.
Martinez-Garcia E, Irigoyen M, Anso E, Martinez-Irujo J, Rouzaut A
Toxicol Appl Pharmacol . 2008 Feb; 228(3):334-42. PMID: 18262213
Cigarette smoking is the major preventable cause of lung cancer in developed countries. Nicotine (3-(1-methyl-2-pyrrolidinyl)-pyridine) is one of the major alkaloids present in tobacco. Besides its addictive properties, its effects...