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Eva Amatya

Explore the profile of Eva Amatya including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 20
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Recent Articles
1.
Amatya E, Subramanian C, Long R, McNamara K, Cohen M, Blagg B
ChemMedChem . 2024 Aug; 19(24):e202400418. PMID: 39153203
Heat Shock Protein 90 (Hsp90) is responsible for the proper folding and maturation of ~400 client protein substrates, many of which are directly associated with the ten hallmarks of cancer....
2.
Amatya E, Subramanian C, Cohen M, Blagg B
RSC Med Chem . 2024 Mar; 15(3):888-894. PMID: 38516588
Inhibition of the Hsp90 C-terminal domain offers a promising opportunity to treat numerous diseases/indications. Furthermore, the development of Hsp90 C-terminal inhibitors (CTIs) is advantageous over N-terminal inhibitors because it avoids...
3.
Amatya E, Blagg B
Bioorg Med Chem Lett . 2022 Dec; 80:129111. PMID: 36549397
Heat shock protein 90 (Hsp90) is a dynamic protein which serves to ensure proper folding of nascent client proteins, regulate transcriptional responses to environmental stress and guide misfolded and damaged...
4.
Meka P, Amatya E, Kaur S, Banerjee M, Zuo A, Dobrowsky R, et al.
Bioorg Med Chem . 2022 Jul; 70:116940. PMID: 35905686
KU-32 (2) and KU-596 (3), are first and second generation cytoprotective novologues that are derivatives of novobiocin (1), a heat shock protein 90 (Hsp90) C-terminal inhibitor. Although 2 and 3...
5.
Talukdar K, Roy S, Amatya E, Sleeper E, Le Magueres P, Jurss J
Inorg Chem . 2020 Apr; 59(9):6087-6099. PMID: 32309933
A series of rhenium(I) -tricarbonyl complexes containing pendent arylamine functionality in the second coordination sphere have been developed and studied as electrocatalysts for carbon dioxide (CO) reduction. Aniline moieties were...