Euphemia Leung
Overview
Explore the profile of Euphemia Leung including associated specialties, affiliations and a list of published articles.
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Articles
96
Citations
1044
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Recent Articles
1.
Wang Y, Leung E, Tomek P
Bioorg Chem
. 2025 Feb;
156:108219.
PMID: 39891998
Tryptophan catabolism along the kynurenine pathway (KP) mediates key physiological functions ranging from immune tolerance to lens UV protection, but the contributory roles and chemical fates of individual KP metabolites...
2.
Rees S, Rees T, Paulin E, Arnerich O, Leung E, Walker C, et al.
RSC Med Chem
. 2025 Jan;
PMID: 39823042
Dysregulation of choline phospholipid metabolism and overexpression of phosphatidylcholine-specific phospholipase C (PC-PLC) is implicated in various cancers. Current known enzyme inhibitors include compounds based on a 2-morpholino-5--benzylamino benzoic acid, or...
3.
Geng T, Tian L, Paek S, Leung E, Chamley L, Wu Z
Pharmaceutics
. 2024 Sep;
16(9).
PMID: 39339242
Extracellular vesicles (EVs) have attracted great attention as promising intracellular drug delivery carriers. While the endocytic pathways of small EVs (sEVs, <200 nm) have been reported, there is limited understanding...
4.
Ameratunga R, Longhurst H, Leung E, Steele R, Lehnert K, Woon S
Clin Immunol
. 2024 Jul;
266:110320.
PMID: 39025346
Vaccine challenge responses are an integral component in the diagnostic evaluation of patients with primary antibody deficiency, including Common Variable Immunodeficiency Disorders (CVID). There are no studies of vaccine challenge...
5.
Odak Z, Marijan S, Radan M, Pilkington L, Cikes Botic M, Barker D, et al.
Int J Mol Sci
. 2024 Jul;
25(13).
PMID: 39000063
Ovarian cancer is among the most prevalent causes of mortality among women. Despite improvements in diagnostic methods, non-specific symptoms and delayed gynecological exams can lead to late-stage ovarian tumor discovery....
6.
Ameratunga R, Jordan A, Lehnert K, Leung E, Mears E, Snell R, et al.
Antiviral Res
. 2024 Apr;
227:105894.
PMID: 38677595
COVID-19 has caused calamitous health, economic and societal consequences. Although several COVID-19 vaccines have received full authorization for use, global deployment has faced political, financial and logistical challenges. The efficacy...
7.
Ameratunga R, Woon S, Leung E, Lea E, Chan L, Mehrtens J, et al.
Semin Arthritis Rheum
. 2024 Feb;
65:152387.
PMID: 38330740
Primary immunodeficiency Disorders (PIDS) are rare, mostly monogenetic conditions which can present to a number of specialties. Although infections predominate in most PIDs, some individuals can manifest autoimmune or inflammatory...
8.
Gao Y, Shelling A, Nolan E, Porter D, Leung E, Wu Z
J Liposome Res
. 2024 Jan;
34(3):489-506.
PMID: 38269490
Breast cancer stem cells (BCSCs) play a key role in therapeutic resistance in breast cancer treatments and disease recurrence. This study aimed to develop a combination therapy loaded with pH-sensitive...
9.
Ameratunga R, Leung E, Woon S, Lea E, Allan C, Chan L, et al.
Clin Immunol
. 2023 Nov;
258:109854.
PMID: 38013164
The original CRISPR Cas9 gene editing system and subsequent innovations offers unprecedented opportunities to correct severe genetic defects including those causing Primary Immunodeficiencies (PIDs). Common Variable Immunodeficiency Disorders (CVID) are...
10.
Eurtivong C, Leung E, Sharma N, Leung I, Reynisson J
Molecules
. 2023 Aug;
28(15).
PMID: 37570610
Phosphatidylcholine-specific phospholipase C (PC-PLC) is an enzyme that catalyzes the formation of the important secondary messengers phosphocholine and diacylglycerol (DAG) from phosphatidylcholine. Although PC-PLC has been linked to the progression...