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Eun-Ju Chang

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Articles 87
Citations 1504
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Recent Articles
1.
Nam H, Park S, Lee G, Kim E, Lee S, Chang H, et al.
Exp Mol Med . 2024 Dec; 56(12):2726-2738. PMID: 39633033
TP53-induced glycolysis and apoptosis regulator (TIGAR) regulates redox homeostasis and provides the intermediates necessary for cell growth by reducing the glycolytic rate. During cellular senescence, cells undergo metabolic rewiring towards...
2.
Kim M, Park H, Choi S, Chang E, Ko J, Yoon J
J Mol Endocrinol . 2024 Sep; 73(4). PMID: 39283923
Pentraxin 3 (PTX3) is a prototypic humoral soluble pattern-recognition molecule known to function in immunity-related inflammation. Given the lack of information on the precise functions of PTX3 in the pathogenesis...
3.
Kim J, Lee J, Im S, Kim B, Kim E, Min H, et al.
Exp Mol Med . 2024 Apr; 56(4):1013-1026. PMID: 38684915
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent because it kills cancer cells while sparing normal cells. However, many cancers, including pancreatic ductal adenocarcinoma (PDAC), exhibit intrinsic...
4.
Yoon D, Choi B, Kim J, Kim E, Chung S, Min H, et al.
BMC Med . 2024 Apr; 22(1):178. PMID: 38679711
No abstract available.
5.
Lee H, Kim S, Chung S, Choi B, Kim J, Yoon D, et al.
Br J Cancer . 2024 Apr; 130(12):1979-1989. PMID: 38643339
Background: Pancreatic ductal adenocarcinoma (PDAC) is an aggressive malignancy with a poor survival rate, largely due to the lack of early diagnosis. Although myeloid cells are crucial in the tumour...
6.
Yoon D, Choi B, Kim J, Kim E, Chung S, Min H, et al.
BMC Med . 2024 Mar; 22(1):122. PMID: 38486246
Background: Patients with fibro-calcific aortic valve disease (FCAVD) have lipid depositions in their aortic valve that engender a proinflammatory impetus toward fibrosis and calcification and ultimately valve leaflet stenosis. Although...
7.
Han A, Shin H, Kwon J, Lee S, Lee S, Kim E, et al.
BMB Rep . 2023 Dec; 57(1):60-65. PMID: 38053293
The CRISPR-Cas9 system has significantly advanced regenerative medicine research by enabling genome editing in stem cells. Due to their desirable properties, mesenchymal stem cells (MSCs) have recently emerged as highly...
8.
Kim Y, Lee J, Lee E, Kim D, Jeong M, Hong S, et al.
Biomedicines . 2023 Oct; 11(10). PMID: 37893130
Nicotine, an abundant molecule in tobacco, has immunomodulatory effects on inflammatory diseases, primarily due to the activation of alpha7 nicotinic acetylcholine receptor (α7 nAChR). We aim to evaluate the expression...
9.
Kim E, Kim J, Chung S, Park J, Yoon D, Min H, et al.
Cell Commun Signal . 2023 Aug; 21(1):213. PMID: 37596575
Background: Toll-like receptor 4 (TLR4) conducts a highly regulated inflammatory process by limiting the extent of inflammation to avoid toxicity and tissue damage, even in bone tissues. Thus, it is...
10.
Park J, Lee J, Ok S, Byun S, Chang E, Yoon S, et al.
Exp Mol Med . 2023 Jul; 55(7):1544-1555. PMID: 37464094
The endoplasmic reticulum (ER) is a subcellular organelle essential for cellular homeostasis. Perturbation of ER functions due to various conditions can induce apoptosis. Chronic ER stress has been implicated in...