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Eugene Tu

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Articles 11
Citations 258
Followers 0
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Recent Articles
1.
Stewart M, Quentel A, Manalo E, Montoya Mira J, Ranganathan S, Branchaud B, et al.
Sci Rep . 2024 Dec; 14(1):31809. PMID: 39738320
Proteases are promising biomarkers for cancer early detection. Their enzymatic activity against peptide substrates allows for their straightforward detection using low-cost tests. However, the complexity of the human proteome makes...
2.
Montoya Mira J, Sapre A, Walker B, Bueno Alvarez J, Gustafson K, Tu E, et al.
Commun Biol . 2021 Sep; 4(1):1130. PMID: 34561533
Cellular circulating biomarkers from the primary tumor such as circulating tumor cells (CTCs) and circulating hybrid cells (CHCs) have been described to harbor tumor-like phenotype and genotype. CHCs are present...
3.
Thompson M, Sarabia Feria N, Yoshioka A, Tu E, Civitci F, Estes S, et al.
Biol Open . 2021 Mar; 10(3). PMID: 33685856
Current methods for non-invasive prostate cancer (PrCa) detection have a high false-positive rate and often result in unnecessary biopsies. Previous work has suggested that urinary volatile organic compound (VOC) biomarkers...
4.
Cetin A, Iyidogan P, Hayashi Y, Wallen M, Vijayan K, Tu E, et al.
ACS Sens . 2018 Mar; 3(3):561-568. PMID: 29488377
We demonstrated a proof-of-principle concept of a label-free platform that enables nucleic acid sequencing by binding methodology. The system utilizes gold surfaces having high fidelity plasmonic nanohole arrays which are...
5.
Star A, Tu E, Niemann J, Gabriel J, Joiner C, Valcke C
Proc Natl Acad Sci U S A . 2006 Jan; 103(4):921-6. PMID: 16418278
We report carbon nanotube network field-effect transistors (NTNFETs) that function as selective detectors of DNA immobilization and hybridization. NTNFETs with immobilized synthetic oligonucleotides have been shown to specifically recognize target...
6.
Wang M, Tu E, Raymond D, Yang J, Zhang H, Hagen N, et al.
Nat Biotechnol . 2004 Dec; 23(1):83-7. PMID: 15608628
Microfluidic-based devices have allowed miniaturization and increased parallelism of many common functions in biological assays; however, development of a practical technology for microfluidic-based fluorescence-activated cell sorting has proved challenging. Although...
7.
Zhang H, Tu E, Hagen N, Schnabel C, Paliotti M, Soo Hoo W, et al.
Biomed Microdevices . 2004 Aug; 6(1):11-21. PMID: 15307440
Optophoresis is a non-invasive cell analysis technique that is based on the interaction of live whole cells with optical gradient fields, typically generated by a near-infrared laser. The magnitude of...
8.
Forster A, Wang M, Butler W, Chachisvilis M, Chung T, Esener S, et al.
Anal Biochem . 2004 Mar; 327(1):14-22. PMID: 15033506
To facilitate quantitation of cellular apoptotic responses to various antineoplastic agents, a laser-based technology, Optophoresis, has been developed to provide analysis of cells without any need for labeling or cell...
9.
Wang M, Schnabel C, Chachisvilis M, Yang R, Paliotti M, Simons L, et al.
Appl Opt . 2003 Oct; 42(28):5765-73. PMID: 14528941
A novel, noninvasive measurement technique for quantitative cellular analysis is presented that utilizes the forces generated by an optical beam to evaluate the physical properties of live cells in suspension....
10.
Sosnowski R, Heller M, Tu E, Forster A, Radtkey R
Psychiatr Genet . 2002 Nov; 12(4):181-92. PMID: 12454523
Microelectronic arrays have been developed for DNA hybridization analysis of point mutations, single nucleotide polymorphisms, short tandem repeats and gene expression. In addition to a variety of molecular biology and...