Eugene Roscioli
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Explore the profile of Eugene Roscioli including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
417
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Recent Articles
1.
Gunn N, Kidd S, Solomon L, Yang D, Roscioli E, Atkins G
Front Cell Infect Microbiol
. 2024 Jun;
14:1403289.
PMID: 38915921
is a major causative pathogen of osteomyelitis. Intracellular infections of resident bone cells including osteocytes can persist despite gold-standard clinical intervention. The mechanisms by which intracellular evades antibiotic therapy are...
2.
Hodge G, Jersmann H, Holmes M, Asare P, Roscioli E, Reynolds P, et al.
Biology (Basel)
. 2023 Sep;
12(9).
PMID: 37759660
Introduction: Pro-inflammatory CD8+ T cells are increased in the lungs and also in the peripheral circulation of both smokers and chronic obstructive pulmonary disease (COPD) patients. The reason for this...
3.
Asare P, Hurtado P, Tran H, Perkins G, Roscioli E, Hodge S
Clin Exp Med
. 2023 Jun;
23(7):4041-4055.
PMID: 37310658
Background: A common feature of COPD is a defective lung macrophage phagocytic capacity that can contribute to chronic lung inflammation and infection. The precise mechanisms remain incompletely understood, although cigarette...
4.
Delhove J, Alawami M, Macowan M, Lester S, Nguyen P, Jersmann H, et al.
Sci Rep
. 2022 Nov;
12(1):19225.
PMID: 36357550
Differentiated air-liquid interface models are the current standard to assess the mucociliary phenotype using clinically-derived samples in a controlled environment. However, obtaining basal progenitor airway epithelial cells (AEC) from the...
5.
Asare P, Tran H, Hurtado P, Perkins G, Nguyen P, Jersmann H, et al.
Ther Adv Respir Dis
. 2021 Dec;
15:17534666211039769.
PMID: 34852704
Introduction/rationale: In chronic obstructive pulmonary disease (COPD), defective macrophage phagocytic clearance of cells undergoing apoptosis by efferocytosis may lead to secondary necrosis of the uncleared cells and contribute to airway...
6.
Gunn N, Zelmer A, Kidd S, Solomon L, Roscioli E, Yang D, et al.
Front Cell Infect Microbiol
. 2021 Nov;
11:781022.
PMID: 34805001
Infectious osteomyelitis associated with periprosthetic joint infections is often recalcitrant to treatment and has a high rate of recurrence. In the case of , the most common pathogen in all...
7.
Asare P, Roscioli E, Hurtado P, Tran H, Mah C, Hodge S
Front Oncol
. 2020 Aug;
10:1298.
PMID: 32850405
One aim of cancer therapies is to induce apoptosis of tumor cells. Efficient removal of the apoptotic cells requires coordinated efforts between the processes of efferocytosis and LC3-associated phagocytosis (LAP)....
8.
Poh W, Kicic A, Lester S, Nguyen P, Bakaletz L, Reynolds P, et al.
Int J Chron Obstruct Pulmon Dis
. 2020 Jun;
15:1253-1260.
PMID: 32581530
Introduction: COPD is an inflammatory airway pathology associated with recurrent infection by nontypeable (NTHi) that is not effectively managed by macrolide antibiotic therapy. We hypothesised that NTHi is able to...
9.
Roscioli E, Hamon R, Lester S, Jersmann H, Reynolds P, Hodge S
Respir Res
. 2018 Nov;
19(1):234.
PMID: 30486816
Background: Individuals with respiratory disease are being increasingly exposed to wildfire smoke as populations encroach further into forested regions and climate change continues to bring higher temperatures with lower rainfall....
10.
Murphy J, Ramezanpour M, Drilling A, Roscioli E, Psaltis A, Wormald P, et al.
Int Forum Allergy Rhinol
. 2018 Nov;
9(2):187-196.
PMID: 30431711
Background: Staphylococcus aureus is a major contributor to the pathophysiology of chronic rhinosinusitis (CRS). Previous research has shown that S. aureus-secreted products disrupt the airway barrier. Methods: S. aureus ATCC...