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Ethan J Brock

Explore the profile of Ethan J Brock including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 208
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Recent Articles
1.
Shah S, Osuala K, Brock E, Ji K, Sloane B, Mattingly R
Cells . 2025 Feb; 14(3). PMID: 39937011
Diagnosis of ductal carcinoma in situ (DCIS) presents a challenge as we cannot yet distinguish between those lesions that remain dormant from cases that may progress to invasive ductal breast...
2.
Brock E, Jackson R, Boerner J, Li Q, Tennis M, Sloane B, et al.
PLoS One . 2021 May; 16(5):e0252314. PMID: 34048471
Breast ductal carcinoma in situ (DCIS) is a non-obligate precursor of invasive ductal carcinoma (IDC). It is still unclear which DCIS will become invasive and which will remain indolent. Patients...
3.
Shah S, Brock E, Jackson R, Ji K, Boerner J, Sloane B, et al.
Neoplasia . 2018 Aug; 20(9):951-963. PMID: 30144784
Diagnosis of breast ductal carcinoma in situ (DCIS) presents a challenge since we cannot yet distinguish those cases that would remain indolent and not require aggressive treatment from cases that...
4.
Brock E, Ji K, Shah S, Mattingly R, Sloane B
J Mammary Gland Biol Neoplasia . 2018 Jul; 24(1):1-15. PMID: 30056557
About one fourth of all newly identified cases of breast carcinoma are diagnoses of breast ductal carcinoma in situ (DCIS). Since we cannot yet distinguish DCIS cases that would remain...
5.
Shah S, Brock E, Ji K, Mattingly R
Semin Cancer Biol . 2018 Apr; 54:29-39. PMID: 29621614
Ras oncoproteins play pivotal roles in both the development and maintenance of many tumor types. Unfortunately, these proteins are difficult to directly target using traditional pharmacological strategies, in part due...
6.
Brock E, Ji K, Reiners J, Mattingly R
Mini Rev Med Chem . 2015 Oct; 16(5):358-69. PMID: 26423696
Oncogenic Ras proteins are a driving force in a significant set of human cancers and wildtype, unmutated Ras proteins likely contribute to the malignant phenotype of many more. The overall...
7.
Leung W, Shaffer C, Reed L, Smith S, Barshop W, Dirkes W, et al.
G3 (Bethesda) . 2015 Mar; 5(5):719-40. PMID: 25740935
The Muller F element (4.2 Mb, ~80 protein-coding genes) is an unusual autosome of Drosophila melanogaster; it is mostly heterochromatic with a low recombination rate. To investigate how these properties...