Estela Sanguesa
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Explore the profile of Estela Sanguesa including associated specialties, affiliations and a list of published articles.
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10
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12
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Recent Articles
1.
Concha J, Sanguesa E, Ribate M, Garcia C
Int J Mol Sci
. 2024 Oct;
25(20).
PMID: 39457109
Tacrolimus (TAC) is a commonly used immunosuppressive drug in solid organ transplantation. Pharmacogenetics has been demonstrated before to be decisive in TAC pharmacotherapy. The variant has been reported to be...
2.
Fernandez-Egea E, Chen S, Sanguesa E, Gasso P, Biria M, Plaistow J, et al.
Br J Psychiatry
. 2024 Apr;
224(5):164-169.
PMID: 38652060
Background: A significant proportion of people with clozapine-treated schizophrenia develop 'checking' compulsions, a phenomenon yet to be understood. Aims: To use habit formation models developed in cognitive neuroscience to investigate...
3.
Sanguesa E, Fernandez-Egea E, Concha J, Garcia C, Ribate M
Biomedicines
. 2024 Mar;
12(3).
PMID: 38540209
Managing schizophrenia with clozapine poses a significant challenge due to prevalent therapeutic failures. The increasing interest in personalized medicine underscores the importance of integrating pharmacogenetic information for effective pharmacotherapeutic monitoring...
4.
Lomba L, Garcia C, Benito L, Sanguesa E, Santander S, Zuriaga E
ACS Biomater Sci Eng
. 2023 Dec;
10(1):178-190.
PMID: 38141007
Cryopreservation of cells, tissues, and organs is widely used in the biomedical and research world. There are different cryopreservatives that are used for this process; however, many of them, such...
5.
Concha J, Sanguesa E, Pena J, Ribate M, Garcia C
Pharmacogenomics
. 2023 Oct;
24(15):797-808.
PMID: 37869874
Tuberous sclerosis complex (TSC) is a rare disease that produces multisystemic disorders. Everolimus (EVR) is the only immunosuppressive drug approved to control the symptoms and progression of the disease. The...
6.
Concha J, Sanguesa E, Saez-Benito A, Aznar I, Berenguer N, Saez-Benito L, et al.
Life (Basel)
. 2023 Aug;
13(8).
PMID: 37629484
Tacrolimus (TAC) is a narrow-therapeutic-range immunosuppressant drug used after organ transplantation. A therapeutic failure is possible if drug levels are not within the therapeutic range after the first year of...
7.
Sanguesa E, Cirujeda C, Concha J, Padilla P, Garcia C, Ribate M
Chem Biol Interact
. 2022 Jul;
364:110042.
PMID: 35853541
The combination of valproic acid (VPA) and clozapine (CLZ) is regularly prescribed for augmentation therapy in treatment resistant schizophrenia. The VPA has been shown to reduce norclozapine (NCLZ) plasma levels,...
8.
Sanguesa E, Cirujeda C, Concha J, Padilla P, Garcia C, Ribate M
Per Med
. 2022 Mar;
19(3):181-192.
PMID: 35259926
The aims of the present study were to assess the variance of plasma clozapine (CLZ) levels and to identify the influence of sociodemographic and pharmacogenetic factors on it and to...
9.
Sanguesa E, Cirujeda C, Concha J, Padilla P, Ribate M, Garcia C
Pharmacogenomics
. 2019 Aug;
20(12):871-877.
PMID: 31453772
We report the case of a young Caucasian male with disorganized chronic schizophrenia, an active smoker and nonresponder to 400 mg of clozapine/day. Therapeutic clozapine monitoring was analyzed revealing a...
10.
Lopez I, Sanguesa E, Vancraenendonck Y, Zuriaga E, Ribate M, Garcia C
Drug Metab Pers Ther
. 2016 Oct;
31(4):191-196.
PMID: 27740916
Vitamin K antagonists are highly effective antithrombotic drugs. However, appropriate dosing is difficult to establish owing to its narrow therapeutic window as well as widespread inter- and intra-individual variability in...