Esmee Vendel
Overview
Explore the profile of Esmee Vendel including associated specialties, affiliations and a list of published articles.
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5
Citations
64
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Recent Articles
1.
Willmann S, Keller A, Meyer M, van der Mey D, Wirsching G, Zhang Y, et al.
Pediatr Pulmonol
. 2022 Dec;
58(3):908-917.
PMID: 36507572
Background: The PATENT-CHILD study investigated riociguat in children aged ≥ 6 to <18 years with pulmonary arterial hypertension (PAH) treated with tablets or an oral pediatric suspension based on bodyweight-adjusted...
2.
Vendel E, Rottschafer V, de Lange E
PLoS One
. 2020 Sep;
15(9):e0238397.
PMID: 32966285
The development of drugs targeting the brain still faces a high failure rate. One of the reasons is a lack of quantitative understanding of the complex processes that govern the...
3.
Vendel E, Rottschafer V, de Lange E
Pharm Res
. 2020 Jul;
37(7):137.
PMID: 32648115
Purpose: We have developed a 3D brain unit network model to understand the spatial-temporal distribution of a drug within the brain under different (normal and disease) conditions. Our main aim...
4.
Vendel E, Rottschafer V, de Lange E
Fluids Barriers CNS
. 2019 May;
16(1):12.
PMID: 31092261
The blood brain barrier (BBB) is the main barrier that separates the blood from the brain. Because of the BBB, the drug concentration-time profile in the brain may be substantially...
5.
Vendel E, de Lange E
Neuromolecular Med
. 2014 Jun;
16(3):620-42.
PMID: 24929655
The cannabinoid (CB) receptors are the main targets of the cannabinoids, which include plant cannabinoids, endocannabinoids and synthetic cannabinoids. Over the last few years, accumulated evidence has suggested a role...