Erwin Tschachler
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Explore the profile of Erwin Tschachler including associated specialties, affiliations and a list of published articles.
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204
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4872
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Recent Articles
11.
Direder M, Weiss T, Copic D, Vorstandlechner V, Laggner M, Pfisterer K, et al.
Matrix Biol
. 2022 Mar;
108:55-76.
PMID: 35278628
Keloids are disfiguring, hypertrophic scars with yet poorly understood pathomechanisms, which could lead to severe functional impairments. Here we analyzed the characteristics of keloidal cells by single cell sequencing and...
12.
Lachner J, Ehrlich F, Wielscher M, Farlik M, Hermann M, Tschachler E, et al.
Sci Rep
. 2022 Jan;
12(1):126.
PMID: 34997067
The growth of skin appendages, such as hair, feathers and scales, depends on terminal differentiation of epidermal keratinocytes. Here, we investigated keratinocyte differentiation in avian scutate scales. Cells were isolated...
13.
NOD2 and reproduction-associated NOD-like receptors have been lost during the evolution of pangolins
Salova M, Sipos W, Tschachler E, Eckhart L
Immunogenetics
. 2021 Nov;
74(2):261-268.
PMID: 34725731
NOD-like receptors (NLRs) are sensors of pathogen-associated molecular patterns with critical roles in the control of immune responses and programmed cell death. Recent studies have revealed inter-species differences in mammalian...
14.
Vorstandlechner V, Laggner M, Copic D, Klas K, Direder M, Chen Y, et al.
Nat Commun
. 2021 Oct;
12(1):6242.
PMID: 34716325
Despite recent advances in understanding skin scarring, mechanisms triggering hypertrophic scar formation are still poorly understood. In the present study, we investigate mature human hypertrophic scars and developing scars in...
15.
Rossiter H, Copic D, Direder M, Gruber F, Zoratto S, Marchetti-Deschmann M, et al.
Autophagy
. 2021 Sep;
18(5):1005-1019.
PMID: 34491140
ATG7: autophagy related 7; BODIPY: boron dipyrromethene; DAG: diacyl glycerides; DBI: diazepam binding inhibitor; GFP: green fluorescent protein; KRT14: keratin 14; HPLC-MS: high performance liquid chromatography-mass spectrometry; LD: lipid droplet;...
16.
Lachner J, Derdak S, Mlitz V, Wagner T, Holthaus K, Ehrlich F, et al.
J Invest Dermatol
. 2021 Jun;
141(12):2829-2837.
PMID: 34116064
The function of the skin as a barrier against a dry environment evolved in a common ancestor of terrestrial vertebrates such as mammals and birds. However, it is unknown which...
17.
Holthaus K, Lachner J, Ebner B, Tschachler E, Eckhart L
Sci Rep
. 2021 Jun;
11(1):12334.
PMID: 34112911
Major protein components of the mammalian skin barrier are encoded by genes clustered in the Epidermal Differentiation Complex (EDC). The skin of cetaceans, i.e. whales, porpoises and dolphins, differs histologically...
18.
Copic D, Laggner M, Kalinina P, Klas K, Tschachler E, Mildner M
Biomedicines
. 2021 Mar;
9(3).
PMID: 33652877
Ichthyoses comprise a broad spectrum of keratinization disorders due to hereditary defects of cornification. Until now, mutations in more than 50 genes, mostly coding for structural proteins involved in epidermal...
19.
Mlitz V, Hermann M, Buchberger M, Tschachler E, Eckhart L
Genes (Basel)
. 2021 Feb;
12(2).
PMID: 33578693
Scaffoldin, an S100 fused-type protein (SFTP) with high amino acid sequence similarity to the mammalian hair follicle protein trichohyalin, has been identified in reptiles and birds, but its functions are...
20.
Cichon M, Klas K, Buchberger M, Hammer M, Sere K, Zenke M, et al.
Front Cell Dev Biol
. 2021 Feb;
8:608876.
PMID: 33542915
The endoplasmic reticulum-associated protein reticulon 1A (RTN1A) is primarily expressed in neuronal tissues but was recently identified also specifically in cells of the dendritic cell (DC) lineage, including epidermal Langerhans...