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Erwin Surmann

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Articles 16
Citations 425
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Recent Articles
1.
Liu Y, Tomlinson B, Guo J, Asgharnejad M, Bauer L, Surmann E, et al.
Clin Ther . 2018 Aug; 40(7):1108-1121.e8. PMID: 30098648
Purpose: The pharmacokinetic (PK) profile of the rotigotine transdermal patch is well characterized in Caucasian patients with Parkinson's disease (PD) but not in Chinese subjects. This article reports the PK...
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Zhang Z, Liu C, Tao E, Shao M, Liu Y, Wang J, et al.
Parkinsonism Relat Disord . 2017 Aug; 44:6-12. PMID: 28827011
Introduction: Rotigotine was demonstrated to be efficacious and well-tolerated in three placebo-controlled studies (CLEOPATRA-PD/PREFER/SP921) of patients with advanced-stage Parkinson's disease (PD), most of whom were Caucasian. This multicenter phase 3...
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Hauser R, Slawek J, Barone P, Dohin E, Surmann E, Asgharnejad M, et al.
BMC Neurol . 2016 Jun; 16:90. PMID: 27267880
Background: This multicenter, double-blind, placebo-controlled study assessed the efficacy of rotigotine transdermal patch on apathy and motor symptoms in patients with Parkinson's disease (PD). Methods: Patients with PD-associated apathy (Unified...
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Zhang Z, Shang H, Hu X, Chen S, Zhao Z, Du X, et al.
Parkinsonism Relat Disord . 2016 May; 28:49-55. PMID: 27172830
Introduction: Two phase3 studies (SP512; SP513) involving mostly Caucasian patients showed that rotigotine (≤8 mg/24 h) was efficacious and welltolerated in early-stage Parkinson's disease (PD). We report results from a...
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Rascol O, Zesiewicz T, Chaudhuri K, Asgharnejad M, Surmann E, Dohin E, et al.
J Clin Pharmacol . 2015 Dec; 56(7):852-61. PMID: 26626320
Pain is a troublesome nonmotor symptom of Parkinson's disease (PD). This double-blind exploratory pilot study (NCT01744496) was the first to specifically investigate the effect of a dopamine agonist on PD-associated...
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Giladi N, Ghys L, Surmann E, Boroojerdi B, Jankovic J
Parkinsonism Relat Disord . 2014 Dec; 20(12):1345-51. PMID: 25444083
Purpose: In two 6-month, double-blind, placebo-controlled studies, rotigotine transdermal system was well-tolerated and efficacious monotherapy in early-stage PD. This post hoc analysis of the long-term open-label extensions (NCT00594165; NCT00599196) of...
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Nicholas A, Borgohain R, Chana P, Surmann E, Thompson E, Bauer L, et al.
J Parkinsons Dis . 2014 Mar; 4(3):361-73. PMID: 24643203
Background: Previous phase III studies in patients with advanced Parkinson's disease (PD) not adequately controlled on levodopa demonstrated significant reduction of 'off' time with rotigotine transdermal system up to 16...
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Kassubek J, Chaudhuri K, Zesiewicz T, Surmann E, Boroojerdi B, Moran K, et al.
BMC Neurol . 2014 Mar; 14:42. PMID: 24602411
Background: Pain is a troublesome non-motor symptom of Parkinson's disease (PD). The RECOVER (Randomized Evaluation of the 24-hour Coverage: Efficacy of Rotigotine; Clintrials.gov: NCT00474058) study demonstrated significant improvements in early-morning...
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Swick T, Friedman J, Chaudhuri K, Surmann E, Boroojerdi B, Moran K, et al.
Eur Neurol . 2014 Jan; 71(3-4):140-7. PMID: 24457253
Background: RECOVER (NCT00474058), a double-blind, placebo-controlled trial in patients with Parkinson's disease (PD) and unsatisfactory early-morning motor symptom control, demonstrated significant improvements with rotigotine in early-morning motor function (Unified Parkinson's...