Erum Shireen
Overview
Explore the profile of Erum Shireen including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
38
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Recent Articles
1.
Shireen E
J Exp Pharmacol
. 2016 Aug;
8:1-10.
PMID: 27540314
Antipsychotic drugs are extensively prescribed for the treatment of schizophrenia and other related psychiatric disorders. These drugs produced their action by blocking dopamine (DA) receptors, and these receptors are widely...
2.
Inam Q, Ikram H, Shireen E, Haleem D
Pak J Pharm Sci
. 2016 May;
29(3):757-63.
PMID: 27166525
Lower levels of 5-hydroxytryptamine (5-HT; serotonin) in the brain elicit sugar craving, while ingestion of sugar rich diet improves mood and alleviates anxiety. Gender differences occur not only in brain...
3.
Shireen E, Pervez S, Masroor M, Ali W, Rais Q, Khalil S, et al.
Pak J Pharm Sci
. 2014 Sep;
27(5 Spec no):1459-66.
PMID: 25176240
Stress is defined as a non specific response of body to any physiological and psychological demand. Preclinical studies have shown that an uncontrollable stress condition produces neurochemical and behavioral deficits....
4.
Inam Q, Shireen E, Haider S, Haleem D
J Ayub Med Coll Abbottabad
. 2014 May;
23(2):97-9.
PMID: 24800354
Background: Examination stress is a psychological stress that activate hypothalamic-pituitary adrenocortical (HPA) axis to increase circulating levels of glucocorticoids. The fat derived hormone leptin is also released in response to...
5.
Shireen E, Naeem S, Inam Q, Haleem D
Pak J Pharm Sci
. 2013 Mar;
26(2):271-6.
PMID: 23455196
The present study was designed to monitor extrapyramidal symptoms (EPS) elicited by the oral administration of haloperidol at clinically recommended doses and to compare it with EPS produced when the...
6.
Shireen E, Haleem D
Pak J Pharm Sci
. 2010 Dec;
24(1):7-12.
PMID: 21190911
Although haloperidol is widely prescribed for the treatment of schizophrenia, its beneficial effects are accompanied by extrapyramidal side effects (EPS). Role of 5-HT-2A/2C receptors in the attenuation of acute Parkinsonian-like...
7.
Shireen E, Qurrat-Ul-Ain , Batool F, Saify Z, Haleem D
Pak J Pharm Sci
. 2006 Jan;
15(1):71-82.
PMID: 16414870
In view of a possible role of presynaptic serotonin (5-hydroxytryptamine, 5-HT) receptors in the precipitation of extrapyramidal side effects (EPS), the present study was designed to investigate the neurochemical effects...
8.
Shireen E, Haleem D
J Coll Physicians Surg Pak
. 2006 Jan;
15(12):753-6.
PMID: 16398963
Objective: To determine the effect of low and high doses of buspirone on motor activity and striatal monoamine metabolism in rats. Design: Experimental study. Place And Duration Of Study: The...
9.
Haleem D, Hasnat A, Shireen E, Khan A, Haleem M
J Coll Physicians Surg Pak
. 2005 Oct;
15(8):458-62.
PMID: 16202354
Objective: To determine the role of dopamine and 5-hydroxytryptamine (5-HT; serotonin) in the reinforcing effects of alcohol and apomorphine. Design: Experimental study. Place And Duration Of Study: Department of Biochemistry,...
10.
Haleem D, Shireen E, Haleem M
Prog Neuropsychopharmacol Biol Psychiatry
. 2004 Dec;
28(8):1323-9.
PMID: 15588759
The mechanism by which stimulation of somatodendritic and/or postsynaptic 5-hydroxytryptamine (5-HT, serotonin)-1A receptor could attenuate acute Parkinsonian-like effects of typical antipsychotics is investigated by comparing the anticataleptic and neurochemical effects...