Ernst-Jan M Speel
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Explore the profile of Ernst-Jan M Speel including associated specialties, affiliations and a list of published articles.
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92
Citations
1951
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Recent Articles
1.
Froyen G, Volders P, Geerdens E, Berden S, Van der Meulen J, De Cock A, et al.
Mol Oncol
. 2025 Jan;
PMID: 39887903
Somatic multigene analysis by next-generation sequencing (NGS) is routinely integrated in medical oncology for clinical decision-making. However, with the fast-growing number of recommended and required genes as well as pan-cancer...
2.
Leunissen D, Moonen L, von der Thusen J, den Bakker M, Hillen L, van Weert T, et al.
J Thorac Oncol
. 2024 Nov;
PMID: 39581377
Introduction: Multi-omic studies have identified three molecular separated pulmonary carcinoid (PC) subgroups (A1, A2, B) with distinctive mRNA expression profiles (e.g., orthopedia homeobox protein [OTP], achaete-scute homolog [ASCL1], and hepatocyte...
3.
Mobaraki G, Shi S, Liu D, Smits K, Severens K, Lommen K, et al.
Int J Mol Sci
. 2024 Aug;
25(15).
PMID: 39125783
Worldwide, the incidence of renal cell carcinoma (RCC) is rising, accounting for approximately 2% of all cancer diagnoses and deaths. The etiology of RCC is still obscure. Here, we assessed...
4.
Demers I, Balaji H, Feitsma H, Stelloo E, Swennenhuis J, Sergeeva I, et al.
J Med Virol
. 2024 Aug;
96(8):e29837.
PMID: 39105417
Human papillomavirus (HPV) infections are an increasing cause of oropharyngeal squamous cell carcinomas (OPSCC). Integration of the viral genome into the host genome is suggested to affect carcinogenesis, however, the...
5.
Speel E, Dafni U, Thunnissen E, Ruschoff J, OBrien C, Kowalski J, et al.
Lung Cancer
. 2024 Jul;
194:107860.
PMID: 39002492
Background: ROS1 fusion is a relatively low prevalence (0.6-2.0%) but targetable driver in lung adenocarcinoma (LUAD). Robust and low-cost tests, such as immunohistochemistry (IHC), are desirable to screen for patients...
6.
van Opijnen M, Broekman M, Cuppen E, Dubbink H, Ter Elst A, van Eijk R, et al.
J Neurooncol
. 2024 Jan;
166(3):485-492.
PMID: 38285243
Purpose: Next generation sequencing (NGS) is an important tool used in clinical practice to obtain the required molecular information for accurate diagnostics of high-grade adult-type diffuse glioma (HGG). Since individual...
7.
Vernemmen A, Samarska I, Speel E, Riedl R, Goudkade D, de Bruine A, et al.
Histopathology
. 2023 Dec;
84(5):794-809.
PMID: 38155480
Aims: Inflammatory myofibroblastic tumour (IMT) is a rare mesenchymal neoplasm of intermediate malignant potential, occurring at any age and at multiple sites. Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is an aggressive...
8.
Heuvelings D, Wintjens A, Moonen L, Engelen S, de Hingh I, Valkenburg-van Iersel L, et al.
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37629011
Metastatic colorectal cancer (CRC) is a common cause of cancer-related mortality, of which peritoneal metastases (PMs) have the worse outcome. Metastasis-specific markers may help predict the spread of tumor cells...
9.
Brouns A, Hendriks L, Robbesom-van den Berge I, Driessen A, Roemen G, van Herpen B, et al.
Front Oncol
. 2023 May;
13:1145001.
PMID: 37213294
Introduction: Bone metastases are frequent in patients with non-small cell lung cancer (NSCLC). The receptor activator of Nuclear Factor κB (RANK)/RANK ligand (RANKL)/osteoprotegerin (OPG) pathway is important in bone metastases...
10.
Heuvelings D, Wintjens A, Luyten J, Wilmink G, Moonen L, Speel E, et al.
Cancers (Basel)
. 2023 Jan;
15(2).
PMID: 36672497
Background: As colorectal cancer (CRC) patients with peritoneal metastases (PM) have a poor prognosis, new treatment options are currently being investigated for CRC patients. Specific biomarkers in the primary tumor...