Ernest Beutler
Overview
Explore the profile of Ernest Beutler including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
115
Citations
3522
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
2.
Truksa J, Gelbart T, Peng H, Beutler E, Beutler B, Lee P
Br J Haematol
. 2009 Sep;
147(4):571-81.
PMID: 19751239
Hepcidin, the master regulator of enteric iron absorption, is controlled by the opposing effects of pathways activated in response to iron excess or iron attenuation. Iron excess is regulated through...
3.
Waalen J, Beutler E
Annu Rev Genomics Hum Genet
. 2009 Sep;
10:431-50.
PMID: 19715441
Genetic testing holds great promise as a screening tool to identify persons at risk for a disease at the presymptomatic stage. However, the complexities of gene-disease associations, even in single-gene...
4.
Lee P, Beutler E
Annu Rev Pathol
. 2009 Apr;
4:489-515.
PMID: 19400694
Hepcidin, a 25-amino-acid antimicrobial peptide, is the central regulator of iron homeostasis. Hepcidin transcription is upregulated by inflammatory cytokines, iron, and bone morphogenetic proteins and is downregulated by iron deficiency,...
5.
Nkhoma E, Poole C, Vannappagari V, Hall S, Beutler E
Blood Cells Mol Dis
. 2009 Feb;
42(3):267-78.
PMID: 19233695
Glucose-6-phosphate deficiency is the most prevalent enzyme deficiency, with an estimated 400 million people affected worldwide. This inherited deficiency causes neonatal hyperbilirubinemia and chronic hemolytic anemia. Although most affected individuals...
6.
Truksa J, Lee P, Beutler E
Blood
. 2008 Nov;
113(3):688-95.
PMID: 18997172
Hepcidin plays a major role in the regulation of iron homeostasis. Several bone morphogenetic proteins (BMPs) are strong inducers of hepcidin (Hamp1, HAMP) expression. Hemojuvelin, a protein critical for maintaining...
7.
Lee P, Rice L, McCarthy J, Beutler E
Blood Cells Mol Dis
. 2008 Oct;
42(1):1-4.
PMID: 18823803
A 55 year old man with a history of chronic hepatitis C infection was found to have severe hemochromatosis: hepatic cirrhosis, cardiomyopathy, arrhythmia, hypogonadism, diabetes and bronzed skin color. After...
8.
Lee P, Gelbart T, Waalen J, Beutler E
Blood Cells Mol Dis
. 2008 Aug;
41(3):252-4.
PMID: 18676162
It has been proposed that the anemia of ageing may be caused, at least in part, by elevated hepcidin levels, representing a response to increased IL-6 levels. Using a recently...
9.
10.
Du X, She E, Gelbart T, Truksa J, Lee P, Xia Y, et al.
Science
. 2008 May;
320(5879):1088-92.
PMID: 18451267
Hepcidin, a liver-derived protein that restricts enteric iron absorption, is the key regulator of body iron content. Several proteins induce expression of the hepcidin-encoding gene Hamp in response to infection...