Erinn L Donnelly
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Explore the profile of Erinn L Donnelly including associated specialties, affiliations and a list of published articles.
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11
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Recent Articles
1.
Cespedes N, Fellows A, Donnelly E, Kaylor H, Coles T, Wild R, et al.
Immunohorizons
. 2024 May;
8(5):371-383.
PMID: 38780542
Our previous work demonstrated that basophils regulate a suite of malaria phenotypes, including intestinal mastocytosis and permeability, the immune response to infection, gametocytemia, and parasite transmission to the malaria mosquito...
2.
Cespedes N, Donnelly E, Hansten G, Fellows A, Dobson M, Kaylor H, et al.
Infect Immun
. 2024 Feb;
92(3):e0036023.
PMID: 38299826
Malaria is strongly predisposed to bacteremia, which is associated with increased gastrointestinal permeability and a poor clinical prognosis. We previously identified mast cells (MCs) as mediators of intestinal permeability in...
3.
Donnelly E, Cespedes N, Hansten G, Wagers D, Briggs A, Lowder C, et al.
Immunohorizons
. 2022 Aug;
6(8):630-641.
PMID: 35985797
We have recently demonstrated that basophils are protective against intestinal permeability during malaria and contribute to reduced parasite transmission to mosquitoes. Given that IL-18 is an early cytokine/alarmin in malaria...
4.
Donnelly E, Cespedes N, Hansten G, Wagers D, Briggs A, Lowder C, et al.
Immunohorizons
. 2022 Aug;
6(8):581-599.
PMID: 35970557
Malaria-induced bacteremia has been shown to result from intestinal mast cell (MC) activation. The appearance of MCs in the ileum and increased intestinal permeability to enteric bacteria are preceded by...
5.
Cespedes N, Donnelly E, Lowder C, Hansten G, Wagers D, Briggs A, et al.
Front Immunol
. 2022 Feb;
13:801120.
PMID: 35154114
An increase in mast cells (MCs) and MCs mediators has been observed in malaria-associated bacteremia, however, the role of these granulocytes in malarial immunity is poorly understood. Herein, we studied...
6.
Wu H, Kirita Y, Donnelly E, Humphreys B
J Am Soc Nephrol
. 2019 Mar;
30(4):714.
PMID: 30867248
No abstract available.
7.
Wu H, Kirita Y, Donnelly E, Humphreys B
J Am Soc Nephrol
. 2018 Dec;
30(1):23-32.
PMID: 30510133
Background: A challenge for single-cell genomic studies in kidney and other solid tissues is generating a high-quality single-cell suspension that contains rare or difficult-to-dissociate cell types and is free of...
8.
Wu H, Uchimura K, Donnelly E, Kirita Y, Morris S, Humphreys B
Cell Stem Cell
. 2018 Nov;
23(6):869-881.e8.
PMID: 30449713
Kidney organoids derived from human pluripotent stem cells have great utility for investigating organogenesis and disease mechanisms and, potentially, as a replacement tissue source, but how closely organoids derived from...
9.
O hAinmhire E, Wu H, Muto Y, Donnelly E, Machado F, Fan L, et al.
Am J Physiol Renal Physiol
. 2018 Oct;
316(1):F63-F75.
PMID: 30303712
Glioma-associated oncogene homolog-1 (Gli1)-positive resident mesenchymal stem cell-like cells are the predominant source of kidney myofibroblasts in fibrosis, but investigating Gli1-positive myofibroblast progenitor activation is hampered by the difficulty of...
10.
Wu H, Malone A, Donnelly E, Kirita Y, Uchimura K, Ramakrishnan S, et al.
J Am Soc Nephrol
. 2018 Jul;
29(8):2069-2080.
PMID: 29980650
Single-cell genomics techniques are revolutionizing our ability to characterize complex tissues. By contrast, the techniques used to analyze renal biopsy specimens have changed little over several decades. We tested the...