Erin M Harberts
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Explore the profile of Erin M Harberts including associated specialties, affiliations and a list of published articles.
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9
Citations
71
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Recent Articles
1.
Haupt R, Baracco L, Harberts E, Loganathan M, Kerstetter L, Krammer F, et al.
Sci Rep
. 2023 Jan;
13(1):715.
PMID: 36639569
Influenza A virus (IAV) is a leading cause of respiratory disease worldwide often resulting in severe morbidity and mortality. We have previously shown that the Bacterial Enzymatic Combinatorial Chemistry (BECC)...
2.
Harberts E, Grubaugh D, Akuma D, Shin S, Ernst R, Brodsky I
Infect Immun
. 2022 Jul;
90(8):e0020122.
PMID: 35862717
Immune sensing of the Gram-negative bacterial membrane glycolipid lipopolysaccharide (LPS) is both a critical component of host defense against bacterial infection and a contributor to the hyperinflammatory response, potentially leading...
3.
Alexander-Floyd J, Bass A, Harberts E, Grubaugh D, Buxbaum J, Brodsky I, et al.
Infect Immun
. 2022 Jul;
90(8):e0020822.
PMID: 35862709
Detection of Gram-negative bacterial lipid A by the extracellular sensor, myeloid differentiation 2 (MD2)/Toll-like receptor 4 (TLR4), or the intracellular inflammasome sensors, CASP4 and CASP5, induces robust inflammatory responses. The...
4.
Haupt R, Harberts E, Kitz R, Strohmeier S, Krammer F, Ernst R, et al.
Vaccine
. 2021 Aug;
39(36):5205-5213.
PMID: 34362603
Influenza A virus (IAV) is a leading cause of respiratory disease worldwide often resulting in hospitalization or death. In this study, TLR4 immunostimulatory molecules, Bacterial Enzymatic Combinatorial Chemistry (BECC) 438...
5.
Chandler C, Harberts E, Pelletier M, Thaipisuttikul I, Jones J, Hajjar A, et al.
Proc Natl Acad Sci U S A
. 2020 Sep;
117(37):22984-22991.
PMID: 32868431
Immune evasion through membrane remodeling is a hallmark of pathogenesis. remodels its membrane during its life cycle as it alternates between mammalian hosts (37 °C) and ambient (21 °C to...
6.
Richard K, Perkins D, Harberts E, Song Y, Gopalakrishnan A, Shirey K, et al.
Vaccine
. 2020 May;
38(27):4298-4308.
PMID: 32389496
Toll-like receptors (TLRs), a family of "pattern recognition receptors," bind microbial and host-derived molecules, leading to intracellular signaling and proinflammatory gene expression. TLR4 is unique in that ligand-mediated activation requires...
7.
Chandler C, Harberts E, Laemmermann T, Zeng Q, Opene B, Germain R, et al.
Infect Immun
. 2018 Jul;
86(9).
PMID: 29986891
Infectious diseases propagated by arthropod vectors, such as tularemia, are commonly initiated via dermal infection of the skin. However, due to the technical difficulties in achieving accurate and reproducible dermal...
8.
Oyler B, Khan M, Smith D, Harberts E, Kilgour D, Ernst R, et al.
J Am Soc Mass Spectrom
. 2018 Apr;
29(6):1230.
PMID: 29687418
In the preceding article "Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate" by Oyler et al., an error in the J5 E. coli LPS...
9.
Oyler B, Khan M, Smith D, Harberts E, Kilgour D, Ernst R, et al.
J Am Soc Mass Spectrom
. 2018 Feb;
29(6):1221-1229.
PMID: 29464544
Recent advances in lipopolysaccharide (LPS) biology have led to its use in drug discovery pipelines, including vaccine and vaccine adjuvant discovery. Desirable characteristics for LPS vaccine candidates include both the...