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Erika Van Landuyt

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Citations 109
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Recent Articles
1.
Thys K, Loza M, Lynn L, Callewaert K, Varma L, Crabbe M, et al.
Sci Rep . 2024 Oct; 14(1):22981. PMID: 39362933
We examined candidate biomarkers for efficacy outcomes in hospitalized COVID-19 patients who were treated with sirukumab, an IL-6 neutralizing antibody, in a randomized, double-blind, placebo-controlled, phase 2 trial. Between May...
2.
Gottlieb R, Clement M, Cook P, Deveikis A, Foong K, Robinson P, et al.
J Infect . 2024 Aug; 89(4):106241. PMID: 39182655
Background: Upregulation of IL-6 has been associated with worse prognosis in COVID-19 patients. Impact on IL-6 signalling has mostly been limited to clinical outcomes in IL-6 receptor antagonist trials. Methods:...
3.
Van Hemelryck S, Van Landuyt E, Hufkens V, Vanveggel S
Antivir Ther . 2024 May; 29(2):13596535241248282. PMID: 38725258
Background: Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) fixed-dose combination (FDC) was developed as a once-daily, complete antiretroviral (ARV) regimen therapy to address the need for simplified protease inhibitor-based ARV regimens. This study assessed...
4.
Van Hemelryck S, Van Landuyt E, Ariyawansa J, Vanveggel S, Palmer M
Clin Pharmacol Drug Dev . 2023 Jun; 12(11):1060-1068. PMID: 37335552
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg is a fixed-dose combination (FDC) for the treatment of HIV-1 infection in adults and adolescents weighing 40 kg or greater. This Phase 1, randomized, open-label,...
5.
DAmico R, Cenoz Gomis S, Moodley R, Van Solingen-Ristea R, Baugh B, Van Landuyt E, et al.
HIV Med . 2022 Aug; 24(2):202-211. PMID: 35945163
Objectives: Physicians could request compassionate use of oral and long-acting (LA) cabotegravir + rilpivirine for people living with HIV-1 under a single-patient request programme supported by ViiV Healthcare and Janssen....
6.
Huhn G, Wilkin A, Mussini C, Spinner C, Jezorwski J, El Ghazi M, et al.
HIV Res Clin Pract . 2021 Feb; 21(6):151-167. PMID: 33528318
Background: Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg was investigated in AMBER (treatment-naïve adults; NCT02431247) and EMERALD (treatment-experienced, virologically-suppressed adults; NCT02269917). Objective: To describe a Week 96 pre-planned subgroup analysis of D/C/F/TAF...
7.
Lathouwers E, Weinsteiger S, Baugh B, Ghys A, Jezorwski J, Mohsine E, et al.
J Med Virol . 2020 Dec; 93(6):3985-3990. PMID: 33300183
In AMBER and EMERALD, darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg demonstrated high virological response and low virological failure (VF) through week 96. Week 96 resistance analyses are presented. Post-baseline samples for...
8.
Orkin C, Eron J, Rockstroh J, Podzamczer D, Esser S, Vandekerckhove L, et al.
AIDS . 2019 Dec; 34(5):707-718. PMID: 31833849
Background: Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg was investigated through 96 weeks in AMBER (NCT02431247). Methods: Treatment-naive, HIV-1-positive adults [screening plasma viral load ≥1000 copies/ml; CD4 cell count >50 cells/μl) were...
9.
Lathouwers E, Wong E, Brown K, Baugh B, Ghys A, Jezorwski J, et al.
AIDS Res Hum Retroviruses . 2019 Sep; 36(1):48-57. PMID: 31516033
Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg is being investigated in two Phase III trials, AMBER (NCT02431247; treatment-naive adults) and EMERALD (NCT02269917; treatment-experienced, virologically suppressed adults). Week 48 AMBER and EMERALD resistance...
10.
Huhn G, Eron J, Girard P, Orkin C, Molina J, DeJesus E, et al.
AIDS Res Ther . 2019 Aug; 16(1):23. PMID: 31464642
Background: Darunavir/cobicistat/emtricitabine/tenofovir alafenamide (D/C/F/TAF) 800/150/200/10 mg is a once-daily, single-tablet regimen for treatment of HIV-1 infection. The efficacy/safety of switching to D/C/F/TAF versus continuing boosted protease inhibitor (bPI) + emtricitabine/tenofovir...