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Erika Francesch-Domenech

Explore the profile of Erika Francesch-Domenech including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 227
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Recent Articles
1.
Evans R, Flores-Borja F, Nassiri S, Miranda E, Lawler K, Grigoriadis A, et al.
Cell Rep . 2019 May; 27(7):1967-1978.e4. PMID: 31091437
Lymphatic vasculature is crucial for metastasis in triple-negative breast cancer (TNBC); however, cellular and molecular drivers controlling lymphovascular metastasis are poorly understood. We define a macrophage-dependent signaling cascade that facilitates...
2.
Cheung A, Opzoomer J, Ilieva K, Gazinska P, Hoffmann R, Mirza H, et al.
Clin Cancer Res . 2018 Aug; 24(20):5098-5111. PMID: 30068707
Highly aggressive triple-negative breast cancers (TNBCs) lack validated therapeutic targets and have high risk of metastatic disease. Folate receptor alpha (FRα) is a central mediator of cell growth regulation that...
3.
Patel N, Weekes D, Drosopoulos K, Gazinska P, Noel E, Rashid M, et al.
Nat Commun . 2018 Mar; 9(1):1044. PMID: 29535384
Triple negative breast cancers (TNBCs) lack recurrent targetable driver mutations but demonstrate frequent copy number aberrations (CNAs). Here, we describe an integrative genomic and RNAi-based approach that identifies and validates...
4.
Braso-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, et al.
Nat Med . 2017 Jun; 23(6):788. PMID: 28586336
No abstract available.
5.
Braso-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, et al.
Nat Med . 2017 Apr; 23(4):526. PMID: 28388604
No abstract available.
6.
Braso-Maristany F, Filosto S, Catchpole S, Marlow R, Quist J, Francesch-Domenech E, et al.
Nat Med . 2016 Nov; 22(11):1303-1313. PMID: 27775704
Triple-negative breast cancers (TNBCs) have poor prognosis and lack targeted therapies. Here we identified increased copy number and expression of the PIM1 proto-oncogene in genomic data sets of patients with...