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Erik M Koenig

Explore the profile of Erik M Koenig including associated specialties, affiliations and a list of published articles. Areas
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Articles 2
Citations 88
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Recent Articles
1.
Koenig E, Fisher C, Bernard H, Wolenski F, Gerrein J, Carsillo M, et al.
BMC Genomics . 2016 Aug; 17:649. PMID: 27535741
Background: MicroRNAs (miRNA) are varied in length, under 25 nucleotides, single-stranded noncoding RNA that regulate post-transcriptional gene expression via translational repression or mRNA degradation. Elevated levels of miRNAs can be...
2.
Milhollen M, Thomas M, Narayanan U, Traore T, Riceberg J, Amidon B, et al.
Cancer Cell . 2012 Mar; 21(3):388-401. PMID: 22439935
MLN4924 is an investigational small-molecule inhibitor of NEDD8-activating enzyme (NAE) in clinical trials for the treatment of cancer. MLN4924 is a mechanism-based inhibitor, with enzyme inhibition occurring through the formation...