Erik K Flemington
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Explore the profile of Erik K Flemington including associated specialties, affiliations and a list of published articles.
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Articles
111
Citations
2865
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Recent Articles
1.
Shekhar R, OGrady T, Keil N, Feswick A, Amador D, Tibbetts S, et al.
Nucleic Acids Res
. 2024 Jun;
52(13):7720-7739.
PMID: 38922687
Kaposi's sarcoma-associated herpesvirus is the etiologic agent of Kaposi's sarcoma and two B-cell malignancies. Recent advancements in sequencing technologies have led to high resolution transcriptomes for several human herpesviruses that...
2.
Dai L, Del Valle L, Miley W, Whitby D, Ochoa A, Flemington E, et al.
Oncogene
. 2024 Jun;
43(30):2372.
PMID: 38890430
No abstract available.
3.
Ungerleider N, Roberts C, OGrady T, Nguyen T, Baddoo M, Wang J, et al.
Nucleic Acids Res
. 2024 Mar;
52(9):5016-5032.
PMID: 38471819
Viruses are master remodelers of the host cell environment in support of infection and virus production. For example, viruses typically regulate cell gene expression through modulating canonical cell promoter activity....
4.
Abdulnour-Nakhoul S, Kolls J, Flemington E, Ungerleider N, Nakhoul H, Song K, et al.
Am J Physiol Gastrointest Liver Physiol
. 2024 Jan;
326(4):G438-G459.
PMID: 38193195
The calcium-sensing receptor (CaSR), a G protein-coupled receptor, regulates Ca concentration in plasma by regulating parathyroid hormone secretion. In other tissues, it is reported to play roles in cellular differentiation...
5.
Magrath J, Flinchum D, Hartono A, Sampath S, OGrady T, Baddoo M, et al.
Oncogenesis
. 2024 Jan;
13(1):2.
PMID: 38177125
Desmoplastic small round cell tumor (DSRCT) is an aggressive pediatric cancer caused by the EWSR1-WT1 fusion oncoprotein. The tumor is refractory to treatment with a 5-year survival rate of only...
6.
Ma T, Jin L, Bai S, Liu Z, Wang S, Shen B, et al.
J Natl Cancer Inst
. 2023 Oct;
116(3):421-433.
PMID: 37847647
Background: Although the fusion of the transmembrane serine protease 2 gene (TMPRSS2) with the erythroblast transformation-specific-related gene (ERG), or TMPRSS2-ERG, occurs frequently in prostate cancer, its impact on clinical outcomes...
7.
Safa F, Rasmussen T, Fontan L, Xia M, Melnick A, Wiestner A, et al.
Haematologica
. 2023 Sep;
109(5):1348-1358.
PMID: 37767562
B-cell acute lymphoblastic leukemia (B-ALL) remains a hard-to-treat disease with a poor prognosis in adults. Mucosa-associated lymphoid tissue lymphoma translocation protein 1 (MALT1) is a para-caspase required for B-cell receptor...
8.
Flemington E, Flemington S, OGrady T, Baddoo M, Nguyen T, Dong Y, et al.
Nucleic Acids Res
. 2023 Mar;
51(7):e42.
PMID: 36864749
As a fundamental aspect of normal cell signaling and disease states, there is great interest in determining alternative splicing (AS) changes in physiologic, pathologic, and pharmacologic settings. High throughput RNA...
9.
OGrady T, Baddoo M, Flemington S, Ishaq E, Ungerleider N, Flemington E
Front Immunol
. 2023 Jan;
13:1060114.
PMID: 36601126
Introduction: B cell activation and differentiation is central to the adaptive immune response. Changes in exon usage can have major impacts on cellular signaling and differentiation but have not been...
10.
Safa F, Rasmussen T, Lobelle-Rich P, Collier S, Milligan N, Schmeig J, et al.
EJHaem
. 2022 Dec;
3(4):1326-1329.
PMID: 36467812
Cell lines represent an essential tool used in preclinical research. Most hematologic malignancies have a wide array of cell lines representing their respective molecular and pathologic spectra. In mantle cell...