Erik Hanko
Overview
Explore the profile of Erik Hanko including associated specialties, affiliations and a list of published articles.
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Articles
6
Citations
45
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Recent Articles
1.
Almaas R, Hanko E, Mollnes T, Rootwelt T
Brain Res
. 2012 May;
1458:12-7.
PMID: 22546346
The mechanisms of neurotoxicity induced by unconjugated bilirubin (UCB) in newborns are incompletely understood. UCB may cause both necrotic and apoptotic neuronal death. We explored UCB toxicity and release of...
2.
Hanko E, Hansen T, Almaas R, Rootwelt T
Brain Res
. 2006 Jul;
1103(1):56-64.
PMID: 16814266
We used human NT2-N neurons to investigate delayed effects of short-term exposure to unconjugated bilirubin (UCB). Cell viability was evaluated with MTT reduction assays and nuclear morphology. A 6-h exposure...
3.
4.
Hanko E, Hansen T, Almaas R, Paulsen R, Rootwelt T
Pediatr Res
. 2005 Dec;
59(1):72-7.
PMID: 16326984
Unconjugated bilirubin (UCB) induces both apoptosis and necrosis in neurons. To investigate the role of caspases and excitotoxicity in UCB-induced cell death, we exposed NT2-N neurons to 5 microM UCB...
5.
Hanko E, Hansen T, Almaas R, Lindstad J, Rootwelt T
Pediatr Res
. 2004 Dec;
57(2):179-84.
PMID: 15611354
Studies on primary cultures of newborn rodent neurons have suggested that neuronal death induced by unconjugated bilirubin (UCB) is mainly apoptotic in nature. We exposed a human teratocarcinoma-derived cell line,...
6.
Hanko E, Tommarello S, Watchko J, Hansen T
Pediatr Res
. 2003 Aug;
54(4):441-5.
PMID: 12904601
P-glycoprotein (P-gp) is an ATP-dependent integral plasma membrane efflux pump, expressed in abundance in brain capillary endothelial cells and astrocytes. P-gp contributes to the blood-brain barrier in limiting the influx...