Erik Ehinger
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Explore the profile of Erik Ehinger including associated specialties, affiliations and a list of published articles.
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21
Citations
765
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Recent Articles
1.
Ehinger E, Darabi A, Visse E, Edvardsson C, Tomasevic G, Cederberg D, et al.
Trials
. 2025 Mar;
26(1):86.
PMID: 40083039
Background: Glioblastoma, IDH wildtype is the most common primary malignant brain tumor in adults. Despite best available treatment, prognosis remains poor. Current standard therapy consists of surgical tumor removal followed...
2.
Ehinger E, Rao A
Cell Chem Biol
. 2024 Feb;
31(2):189-192.
PMID: 38364775
In this issue of Cell Chemical Biology, Lane et al. introduce a transgene-based system to express fusion proteins that recruit transcription factors to E3 ligases. This approach expands the target...
3.
Lin J, Ehinger E, Hanna D, Qi Q, Wang T, Ghosheh Y, et al.
PLoS One
. 2023 May;
18(5):e0285926.
PMID: 37205656
Persistent inflammation contributes to the development of cardiovascular disease (CVD) as an HIV-associated comorbidity. Innate immune cells such as monocytes are major drivers of inflammation in men and women with...
4.
Ehinger E, Kopecky J, Darabi A, Visse E, Edvardsson C, Tomasevic G, et al.
BMC Neurol
. 2023 Feb;
23(1):76.
PMID: 36803465
Purpose: Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. Despite the best available treatment, prognosis remains poor. Current standard therapy consists of surgical removal of the...
5.
Vallejo J, Saigusa R, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
BMC Biol
. 2022 Oct;
20(1):237.
PMID: 36266696
No abstract available.
6.
Vallejo J, Saigusa R, Gulati R, Suthahar S, Suryawanshi V, Alimadadi A, et al.
BMC Biol
. 2022 Aug;
20(1):193.
PMID: 36045343
Background: Cryopreserved peripheral blood mononuclear cells (PBMCs) are frequently collected and provide disease- and treatment-relevant data in clinical studies. Here, we developed combined protein (40 antibodies) and transcript single-cell (sc)RNA...
7.
Bone Marrow Transplantation Rescues Monocyte Recruitment Defect and Improves Cystic Fibrosis in Mice
Fan Z, Pitmon E, Wen L, Miller J, Ehinger E, Herro R, et al.
J Immunol
. 2022 Jan;
208(3):745-752.
PMID: 35031577
Cystic fibrosis (CF) is an inherited life-threatening disease accompanied by repeated lung infections and multiorgan inflammation that affects tens of thousands of people worldwide. The causative gene, cystic fibrosis transmembrane...
8.
Winkels H, Ghosheh Y, Kobiyama K, Kiosses W, Orecchioni M, Ehinger E, et al.
J Immunol
. 2021 Nov;
207(11):2720-2732.
PMID: 34740961
Double-positive CD4CD8αβ (DP) cells are thought to reside as T cell progenitors exclusively within the thymus. We recently discovered an unexpected CD4 and CD8αβ immune cell population in healthy and...
9.
Buscher K, Heitplatz B, Van Marck V, Song J, Loismann S, Rixen R, et al.
J Am Soc Nephrol
. 2021 Jun;
32(8):1933-1945.
PMID: 34078665
Background: In transplant medicine, clinical decision making largely relies on histology of biopsy specimens. However, histology suffers from low specificity, sensitivity, and reproducibility, leading to suboptimal stratification of patients. We...
10.
Wolf D, Gerhardt T, Winkels H, Michel N, Pramod A, Ghosheh Y, et al.
Circulation
. 2020 Jul;
142(13):1279-1293.
PMID: 32703007
Background: Throughout the inflammatory response that accompanies atherosclerosis, autoreactive CD4 T-helper cells accumulate in the atherosclerotic plaque. Apolipoprotein B (apoB), the core protein of low-density lipoprotein, is an autoantigen that...