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Eric Seidel

Explore the profile of Eric Seidel including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 172
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Recent Articles
1.
Stolting G, Dinh H, Volkert M, Hellmig N, Schewe J, Hennicke L, et al.
JCI Insight . 2023 Sep; 8(20. PMID: 37698934
Somatic gain-of-function mutations in the L-type calcium channel CaV1.3 (CACNA1D gene) cause adrenal aldosterone-producing adenomas and micronodules. De novo germline mutations are found in a syndrome of primary aldosteronism, seizures,...
2.
Muller F, Lim J, Bebber C, Seidel E, Tishina S, Dahlhaus A, et al.
Cell Death Differ . 2022 Nov; 30(2):442-456. PMID: 36443441
Oncogenic KRAS is the key driver oncogene for several of the most aggressive human cancers. One key feature of oncogenic KRAS expression is an early increase in cellular reactive oxygen...
3.
Seidel E, von Karstedt S
Cell Death Discov . 2022 Nov; 8(1):465. PMID: 36435845
Human cancers are known to adhere to basic evolutionary principles. During their journey from early transformation to metastatic disease, cancer cell populations have proven to be remarkably adaptive to different...
4.
Schewe J, Seidel E, Forslund S, Marko L, Peters J, Muller D, et al.
Nat Commun . 2022 May; 13(1):3066. PMID: 35624117
No abstract available.
5.
Karl M, Hasselwander S, Zhou Y, Reifenberg G, Kim Y, Park K, et al.
Hepatology . 2022 Feb; 76(4):1135-1149. PMID: 35218234
Background And Aims: Growing evidence suggests an important role of B cells in the development of NAFLD. However, a detailed functional analysis of B cell subsets in NAFLD pathogenesis is...
6.
Seidel E, Schewe J, Zhang J, Dinh H, Forslund S, Marko L, et al.
Proc Natl Acad Sci U S A . 2021 Apr; 118(17). PMID: 33879608
Gain-of-function mutations in the gene (encoding the T-type calcium channel Ca3.2) cause autosomal-dominant familial hyperaldosteronism type IV (FH-IV) and early-onset hypertension in humans. We used CRISPR/Cas9 to generate knockin mice...
7.
Kumarasamy A, Jeyarajan S, Cheon J, Premceski A, Seidel E, Kimler V, et al.
Exp Eye Res . 2020 Apr; 194:107990. PMID: 32307097
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/about/our-business/policies/article-withdrawal). This article has been retracted at the request of the authors. The senior author contacted the journal...
8.
Seidel E, Walenda G, Messerschmidt C, Obermayer B, Peitzsch M, Wallace P, et al.
Endocr Connect . 2020 Jan; 9(2):122-134. PMID: 31910152
Mitotane is the only drug approved for the therapy of adrenocortical carcinoma (ACC). Its clinical use is limited by the occurrence of relapse during therapy. To investigate the underlying mechanisms...
9.
Schewe J, Seidel E, Forslund S, Marko L, Peters J, Muller D, et al.
Nat Commun . 2019 Nov; 10(1):5155. PMID: 31727896
Gain-of-function mutations in the chloride channel ClC-2 were recently described as a cause of familial hyperaldosteronism type II (FH-II). Here, we report the generation of a mouse model carrying a...
10.
Seidel E, Schewe J, Scholl U
Exp Mol Med . 2019 Nov; 51(11):1-12. PMID: 31695023
Primary aldosteronism is characterized by at least partially autonomous production of the adrenal steroid hormone aldosterone and is the most common cause of secondary hypertension. The most frequent subforms are...