Eric L Allen
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Explore the profile of Eric L Allen including associated specialties, affiliations and a list of published articles.
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5
Citations
768
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Recent Articles
1.
Mahoney C, Pirman D, Chubukov V, Sleger T, Hayes S, Fan Z, et al.
Nat Commun
. 2019 Jan;
10(1):96.
PMID: 30626880
Aberrant metabolism of cancer cells is well appreciated, but the identification of cancer subsets with specific metabolic vulnerabilities remains challenging. We conducted a chemical biology screen and identified a subset...
2.
Allen E, Ulanet D, Pirman D, Mahoney C, Coco J, Si Y, et al.
Cell Rep
. 2016 Oct;
17(3):876-890.
PMID: 27732861
Although aberrant metabolism in tumors has been well described, the identification of cancer subsets with particular metabolic vulnerabilities has remained challenging. Here, we conducted an siRNA screen focusing on enzymes...
3.
Patra K, Wang Q, Bhaskar P, Miller L, Wang Z, Wheaton W, et al.
Cancer Cell
. 2013 Aug;
24(2):213-228.
PMID: 23911236
Accelerated glucose metabolism is a common feature of cancer cells. Hexokinases catalyze the first committed step of glucose metabolism. Hexokinase 2 (HK2) is expressed at high level in cancer cells,...
4.
Wang G, Chen H, Oktay Y, Zhang J, Allen E, Smith G, et al.
Cell
. 2010 Aug;
142(3):456-67.
PMID: 20691904
RNA import into mammalian mitochondria is considered essential for replication, transcription, and translation of the mitochondrial genome but the pathway(s) and factors that control this import are poorly understood. Previously,...
5.
Frank M, Dawson D, Bensinger S, Hong J, Knosp W, Xu L, et al.
Blood
. 2009 Jan;
113(11):2478-87.
PMID: 19147787
B-cell lymphoma is the most common immune system malignancy. TCL1 transgenic mice (TCL1-tg), in which TCL1 is ectopically expressed in mature lymphocytes, develop multiple B- and T-cell leukemia and lymphoma...