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Eric Ispanovic

Explore the profile of Eric Ispanovic including associated specialties, affiliations and a list of published articles. Areas
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Articles 8
Citations 190
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Recent Articles
1.
Whiteside C, Munk S, Ispanovic E, Wang H, Goldberg H, Kapus A, et al.
Nephron Exp Nephrol . 2008 Jul; 109(2):e46-56. PMID: 18600029
Background/aims: We postulated that alpha-smooth muscle actin expressed in primary cultured mesangial cells is down-regulated in 3-dimensional (D) culture and up-regulated by high glucose and growth factors. Methods: Primary rat...
2.
Ispanovic E, Serio D, Haas T
Am J Physiol Cell Physiol . 2008 Jun; 295(3):C600-10. PMID: 18562481
Proteolysis of the basement membrane and interstitial matrix occurs early in the angiogenic process and requires matrix metalloproteinase (MMP) activity. Skeletal muscle microvascular endothelial cells exhibit robust actin stress fibers,...
3.
Uchida C, Gee E, Ispanovic E, Haas T
Cell Biol Int . 2008 May; 32(7):769-76. PMID: 18455449
Angiogenesis (the growth of new capillaries) occurs in adults in response to physiological stimuli such as wound healing and exercise. The mitogen-activated protein kinase c-jun N-terminal kinase (JNK) has a...
4.
Milkiewicz M, Doyle J, Fudalewski T, Ispanovic E, Aghasi M, Haas T
J Physiol . 2007 Jul; 583(Pt 2):753-66. PMID: 17627993
Angiogenesis, which is essential for the physiological adaptation of skeletal muscle to exercise, occurs in response to the mechanical forces of elevated capillary shear stress and cell stretch. Increased production...
5.
Milkiewicz M, Mohammadzadeh F, Ispanovic E, Gee E, Haas T
J Cell Biochem . 2006 Oct; 100(3):750-61. PMID: 17031856
VEGF and MMP protein production are both required for exercise-induced capillary growth in skeletal muscle. The underlying process by which muscle activity initiates an angiogenic response is not established, but...
6.
Ispanovic E, Haas T
Am J Physiol Cell Physiol . 2006 May; 291(4):C579-88. PMID: 16672691
Increased production and activation of matrix metalloproteinase-2 (MMP-2) are critical events in skeletal muscle angiogenesis and are known to occur in response to mechanical stresses. We hypothesized that reorganization of...
7.
Milkiewicz M, Ispanovic E, Doyle J, Haas T
Int J Biochem Cell Biol . 2005 Nov; 38(3):333-57. PMID: 16309946
Angiogenesis provides a mechanism by which delivery of oxygen and nutrients is adapted to compliment changes in tissue mass or metabolic activity. However, maladaptive angiogenesis is integral to the process...
8.
Dlugosz J, Munk S, Ispanovic E, Goldberg H, Whiteside C
Am J Physiol Renal Physiol . 2001 Dec; 282(1):F151-63. PMID: 11739123
In high glucose (HG), mesangial cells (MCs) lose their contractile response to endothelin-1 (ET-1) coincidently with filamentous (F)-actin disassembly. We postulated that these MC phenotypic changes are mediated by altered...