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Eric Dumas de la Roque

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Articles 17
Citations 871
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Recent Articles
1.
Renesme L, Dumas de la Roque E, Germain C, Chevrier A, Rebola M, Cramaregeas S, et al.
Pediatr Pulmonol . 2020 Jul; 55(10):2617-2623. PMID: 32609946
Objective: To determine if nasal high-frequency percussive ventilation (nHFPV) to manage neonatal respiratory distress decreases the regional cerebral oxygen saturation (rScO ) compared to nasal continous positive airway pressure (nCPAP)....
2.
Bouvard C, Genet N, Phan C, Rode B, Thuillet R, Tu L, et al.
Eur Respir J . 2019 Dec; 55(3). PMID: 31862763
The mechanisms underlying pulmonary hypertension (PH) are complex and multifactorial, and involve different cell types that are interconnected through gap junctional channels. Although connexin (Cx)-43 is the most abundant gap...
3.
Dumas de la Roque E, Smeralda G, Quignard J, Freund-Michel V, Courtois A, Marthan R, et al.
PLoS One . 2017 Feb; 12(2):e0173044. PMID: 28235094
Bronchopulmonary dysplasia (BPD) consists of an arrest of pulmonary vascular and alveolar growth, with persistent hypoplasia of the pulmonary microvasculature and alveolar simplification. In 25 to 40% of the cases,...
4.
Dumas de la Roque E, Quignard J, Ducret T, Dahan D, Courtois A, Begueret H, et al.
Pediatr Res . 2013 May; 74(2):163-9. PMID: 23648417
Background: Pulmonary hypertension (PH) is a disease that affects the adult or infant population. Dehydroepiandrosterone (DHEA), a steroid hormone, has been previously shown to prevent and to reverse PH in...
5.
Savineau J, Marthan R, Dumas de la Roque E
Biochem Pharmacol . 2012 Dec; 85(6):718-26. PMID: 23270992
Dehydroepiandrosterone (DHEA) is a steroid hormone derived from cholesterol synthesized by the adrenal glands. DHEA and its 3β-sulphate ester (DHEA-S) are the most abundant circulating steroid hormones. In human, there...
6.
Renesme L, Elleau C, Nolent P, Fayon M, Marthan R, Dumas de la Roque E
Pediatr Pulmonol . 2012 May; 48(3):257-64. PMID: 22570113
Background: Meconium aspiration syndrome (MAS) remains a frequent cause of morbidity and mortality in term newborns. Our objective was to compare two modes of high-frequency ventilation, high-frequency oscillation (HFOV), and...
7.
Dumas de la Roque E, Bellance N, Rossignol R, Begueret H, Billaud M, Santos P, et al.
Eur Respir J . 2012 Apr; 40(6):1420-9. PMID: 22523357
Dehydroepiandrosterone (DHEA) prevents chronic hypoxia-induced pulmonary hypertension and associated right ventricle dysfunction in rats. In this animal model, reoxygenation following hypoxia reverses pulmonary hypertension but not right ventricle dysfunction. We...
8.
Dumas de la Roque E, Savineau J, Metivier A, Billes M, Kraemer J, Doutreleau S, et al.
Ann Endocrinol (Paris) . 2012 Jan; 73(1):20-5. PMID: 22280813
Objectives: It was previously shown that dehydroepiandrosterone (DHEA) reverses chronic hypoxia-induced pulmonary hypertension (PH) in rats, but whether DHEA can improve the clinical and hemodynamic status of patients with PH...
9.
Paulin R, Courboulin A, Meloche J, Mainguy V, Dumas de la Roque E, Saksouk N, et al.
Circulation . 2011 Mar; 123(11):1205-15. PMID: 21382889
Background: Pulmonary artery hypertension (PAH) is a proliferative disorder associated with enhanced pulmonary artery smooth muscle cell proliferation and suppressed apoptosis. The sustainability of this phenotype required the activation of...
10.
Dumas de la Roque E, Bertrand C, Tandonnet O, Rebola M, Roquand E, Renesme L, et al.
Pediatr Pulmonol . 2010 Oct; 46(3):218-23. PMID: 20963833
Objective: To determine whether nasal high frequency percussive ventilation (NHFPV) would decrease duration of transient tachypnea of the newborn (TTN) compared to nasal continuous positive airway pressure (NCPAP) in newborn...