Eoin C OBrien
Overview
Explore the profile of Eoin C OBrien including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
13
Citations
283
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Carlile S, Cahill S, OBrien E, Neto N, Monaghan M, McLoughlin R
iScience
. 2024 Dec;
27(12):111284.
PMID: 39618498
can induce trained immunity in murine macrophages offering protection against repeat exposure during skin infection. Here we demonstrate that exposure can result in non-specific trained immunity in humans and mice,...
2.
Kelly A, McCarthy K, Claxton T, Carlile S, OBrien E, Vozza E, et al.
JCI Insight
. 2024 Jul;
9(13).
PMID: 38973612
Staphylococcus aureus is a major human pathogen. An effective anti-S. aureus vaccine remains elusive as the correlates of protection are ill-defined. Targeting specific T cell populations is an important strategy...
3.
Oleszycka E, OBrien E, Freeley M, Lavelle E, Long A
Front Immunol
. 2023 Dec;
14:1285357.
PMID: 38090554
Bile acids are amphipathic molecules that are synthesized from cholesterol in the liver and facilitate intestinal absorption of lipids and nutrients. They are released into the small intestine upon ingestion...
4.
Mulcahy M, OBrien E, OKeeffe K, Vozza E, Leddy N, McLoughlin R
Front Immunol
. 2020 Dec;
11:565545.
PMID: 33262756
Polymorphonuclear neutrophils (PMN) are critical for first line innate immune defence against . Mature circulating PMN maintain a short half-life ending in constitutive apoptotic cell death. This makes them unlikely...
5.
OBrien E, White C, Wyse J, Leacy E, Porter R, Little M, et al.
Front Med (Lausanne)
. 2020 Oct;
7:553.
PMID: 33015103
Clinical and experimental data suggest that pathogenesis in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis is driven by ANCA-mediated activation of neutrophils and monocytes. While the role of neutrophils has been extensively...
6.
Duggan S, Laabei M, Alnahari A, OBrien E, Lacey K, Bacon L, et al.
Infect Immun
. 2020 Jun;
88(9).
PMID: 32571989
is a major human pathogen, and the emergence of antibiotic-resistant strains is making all types of infections more challenging to treat. With a pressing need to develop alternative control strategies...
7.
OBrien E, McLoughlin R
Trends Mol Med
. 2019 Feb;
25(3):171-184.
PMID: 30713007
Staphylococcus aureus is an opportunistic pathogen, which can readily develop antibiotic resistance and result in severe disease. To combat antibiotic resistance, new treatment strategies are being developed with a particular...
8.
Dooley D, van Timmeren M, OReilly V, Brady G, OBrien E, Fazekas B, et al.
Kidney Int
. 2018 Aug;
94(5):926-936.
PMID: 30158055
Current therapies for treating antineutrophil cytoplasm autoantibody (ANCA)-associated vasculitis include cyclophosphamide and corticosteroids. Unfortunately, these agents are associated with severe adverse effects, despite inducing remission in most patients. Histone deacetylase...
9.
Tobin L, Mavinkurve M, Carolan E, Kinlen D, OBrien E, Little M, et al.
JCI Insight
. 2017 Dec;
2(24).
PMID: 29263296
Childhood obesity is a major global concern, with over 50 million children now classified as obese. Obesity has been linked to the development of numerous chronic inflammatory diseases, including type...
10.
Al-Ani B, Fitzpatrick M, Al-Nuaimi H, Coughlan A, Hickey F, Pusey C, et al.
Sci Rep
. 2016 Dec;
6:38074.
PMID: 27905491
Current biomarkers of renal disease in systemic vasculitis lack predictive value and are insensitive to early damage. To identify novel biomarkers of renal vasculitis flare, we analysed the longitudinal urinary...