Enrique Rodriguez-Boulan
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Explore the profile of Enrique Rodriguez-Boulan including associated specialties, affiliations and a list of published articles.
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66
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3432
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Recent Articles
1.
Ruturaj , Mishra M, Saha S, Maji S, Rodriguez-Boulan E, Schreiner R, et al.
J Cell Sci
. 2023 Nov;
137(5).
PMID: 38032054
The homologous P-type copper-ATPases (Cu-ATPases) ATP7A and ATP7B are the key regulators of copper homeostasis in mammalian cells. In polarized epithelia, upon copper treatment, ATP7A and ATP7B traffic from the...
2.
Lehmann G, Ginsberg M, Nolan D, Rodriguez C, Martinez-Gonzalez J, Zeng S, et al.
Cells
. 2022 Oct;
11(19).
PMID: 36230937
Alpha-2-macroglobulin (A2M) is a protease inhibitor that regulates extracellular matrix (ECM) stability and turnover. Here, we show that A2M is expressed by endothelial cells (ECs) from human eye choroid. We...
3.
Kar S, Sen S, Maji S, Saraf D, Ruturaj , Paul R, et al.
J Biol Chem
. 2022 Jan;
298(3):101631.
PMID: 35090891
Copper(I) is an essential metal for all life forms. Though Cu(II) is the most abundant and stable state, its reduction to Cu(I) via an unclear mechanism is prerequisite for its...
4.
Pan C, Banerjee K, Lehmann G, Almeida D, Hajjar K, Benedicto I, et al.
Proc Natl Acad Sci U S A
. 2021 Nov;
118(47).
PMID: 34782457
Lipofuscin granules enclose mixtures of cross-linked proteins and lipids in proportions that depend on the tissue analyzed. Retinal lipofuscin is unique in that it contains mostly lipids with very little...
5.
Hanke-Gogokhia C, Lehmann G, Benedicto I, De la Fuente-Ortega E, Arshavsky V, Schreiner R, et al.
FASEB J
. 2021 Jun;
35(7):e21689.
PMID: 34085737
Knockout of the chloride channel protein 2 (CLC-2; CLCN2) results in fast progressing blindness in mice. Retinal Pigment Epithelium (RPE) and photoreceptors undergo, in parallel, rapid, and profound morphological changes...
6.
Giovinazzo J, Thomson R, Khalizova N, Zager P, Malani N, Rodriguez-Boulan E, et al.
Elife
. 2020 May;
9.
PMID: 32427098
Recently evolved alleles of Apolipoprotein L-1 () provide increased protection against African trypanosome parasites while also significantly increasing the risk of developing kidney disease in humans. APOL1 protects against trypanosome...
7.
Rodriguez-Boulan E, Misek D, Salas D, Salas P, Bard E
Curr Top Membr Transp
. 2020 Apr;
24:251-294.
PMID: 32287478
This chapter focuses on protein sorting in the secretory pathway. From primary and secondary biosynthetic sites in the cytosol and mitochondrial matrix, respectively, proteins and lipids are distributed to more...
8.
Lehmann G, Hanke-Gogokhia C, Hu Y, Bareja R, Salfati Z, Ginsberg M, et al.
J Exp Med
. 2020 Mar;
217(6).
PMID: 32196081
The activity and survival of retinal photoreceptors depend on support functions performed by the retinal pigment epithelium (RPE) and on oxygen and nutrients delivered by blood vessels in the underlying...
9.
Jonker C, Deo C, Zager P, Tkachuk A, Weinstein A, Rodriguez-Boulan E, et al.
J Cell Sci
. 2019 Dec;
133(2).
PMID: 31843759
The fast turnover of membrane components through endocytosis and recycling allows precise control of the composition of the plasma membrane. Endocytic recycling can be rapid, with some molecules returning to...
10.
Caceres P, Rodriguez-Boulan E
Curr Opin Cell Biol
. 2019 Sep;
62:37-45.
PMID: 31518914
The polarized phenotype of the retinal pigment epithelium is crucial for the outer retina-blood barrier and support of photoreceptors and underlying choroid, and its disruption plays a central role in...