Enrique Dominguez-Alvarez
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Explore the profile of Enrique Dominguez-Alvarez including associated specialties, affiliations and a list of published articles.
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35
Citations
358
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Recent Articles
1.
Kincses A, Szemeredi N, Benito-Lama M, Dozsai D, Csonka A, Dominguez-Alvarez E, et al.
ChemMedChem
. 2024 Nov;
20(2):e202400691.
PMID: 39565046
In recent years, selenocompounds have gained increasing attention as potential anticancer and antibacterial agents. Several selenoderivatives have been confirmed to act as MDR efflux pump inhibitors, based on their in ...
2.
Radomska D, Czarnomysy R, Marciniec K, Nowakowska J, Dominguez-Alvarez E, Bielawski K
Int J Mol Sci
. 2024 Sep;
25(17).
PMID: 39273679
Breast cancer has the highest incidence rate among all malignancies worldwide. Its high mortality is mainly related to the occurrence of multidrug resistance, which significantly limits therapeutic options. In this...
3.
Radomska D, Czarnomysy R, Szymanowska A, Radomski D, Chalecka M, Surazynski A, et al.
Int J Mol Sci
. 2024 Jul;
25(14).
PMID: 39063006
Breast cancer is a major malignancy among women, characterized by a high mortality rate. The available literature evidence indicates that selenium, as a trace element, has chemopreventive properties against many...
4.
Grman M, Balis P, Berenyiova A, Svajdlenkova H, Tomasova L, Cacanyiova S, et al.
Biol Trace Elem Res
. 2024 Apr;
203(2):903-929.
PMID: 38676879
Selenium compounds exert their antioxidant activity mostly when the selenium atom is incorporated into selenoproteins. In our work, we tested the possibility that selenite itself interacts with thiols to form...
5.
Racz B, Kristof E, Kincses A, Dominguez-Alvarez E, Spengler G
Anticancer Res
. 2023 Nov;
43(11):4865-4872.
PMID: 37909996
Background/aim: Previously, selenocompounds (Se-compounds) and in particular selenoesters have shown promising anticancer activities. Since molecular symmetry can enhance the anticancer activity, nine symmetrical selenoesters (Se-esters) have been designed as novel,...
6.
Marc M, Dominguez-Alvarez E, Jacob C
Molecules
. 2023 Aug;
28(16).
PMID: 37630211
Bioorganic Chemistry is an emerging field developing at the interface between the traditional fields of Chemistry and Biochemistry [...].
7.
Balis P, Berenyiova A, Misak A, Grman M, Rostakova Z, Waczulikova I, et al.
Molecules
. 2023 Jun;
28(12).
PMID: 37375381
Phthalic selenoanhydride (R-Se) solved in physiological buffer releases various reactive selenium species including HSe. It is a potential compound for Se supplementation which exerts several biological effects, but its effect...
8.
Zagrodzki P, Wiesner A, Marcinkowska M, Jamrozik M, Dominguez-Alvarez E, Bierla K, et al.
Molecules
. 2023 Mar;
28(5).
PMID: 36903308
Due to problems with selenium deficiency in humans, the search for new organic molecules containing this element in plant biofortification process is highly required. Selenium organic esters evaluated in this...
9.
Racz B, Kincses A, Laczi K, Rakhely G, Dominguez-Alvarez E, Spengler G
Pharmaceutics
. 2023 Feb;
15(2).
PMID: 36839934
Recently, selenium containing derivatives have attracted more attention in medicinal chemistry. In the present work, the anticancer activity of symmetrical selenoesters was investigated by studying the reversal of efflux pump-related...
10.
Radomska D, Czarnomysy R, Szymanowska A, Radomski D, Dominguez-Alvarez E, Bielawska A, et al.
Cancers (Basel)
. 2022 Sep;
14(17).
PMID: 36077839
Disturbing cancer statistics, especially for breast cancer, are becoming a rationale for the development of new anticancer therapies. For the past several years, studies have been proving a greater role...