Enrico Heffler
Overview
Explore the profile of Enrico Heffler including associated specialties, affiliations and a list of published articles.
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250
Citations
3239
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Recent Articles
1.
Larenas-Linnemann D, Rhee C, Altraja A, Busby J, Tran T, Wang E, et al.
Tuberc Respir Dis (Seoul)
. 2025 Feb;
PMID: 39915034
The International Severe Asthma Registry (ISAR) was established in 2017 to advance the understanding of severe asthma and its management, thereby improving patient care worldwide. As the first global registry...
2.
Anastasi F, Canevari F, Gallo S, Gramellini G, Heffler E, La Mantia I, et al.
Front Allergy
. 2025 Jan;
5():1519069.
PMID: 39840273
Background: Chronic rhinosinusitis with nasal polyps (CRSwNP) is an inflammatory condition characterized by persistent nasal obstruction, discharge, facial pressure, and olfactory dysfunction. CRSwNP significantly impairs quality of life (QoL), with...
3.
Canonica G, Blasi F, Paggiaro P, Heffler E, Braido F, Brussino L, et al.
World Allergy Organ J
. 2025 Jan;
18(1):101016.
PMID: 39829953
Background: This study aimed to evaluate the impact of severe asthma (SA) treatments after 12 months in achieving clinical remission (CR) within the context of the Severe Asthma Network in...
4.
Paoletti G, Nappi E, Bragato M, Valli P, Giovannini M, Gargano D, et al.
World Allergy Organ J
. 2025 Jan;
18(1):101015.
PMID: 39810828
Background: Allergen immunotherapy (AIT) is the only treatment that modifies the natural course of allergies. However, AIT is only used in some eligible patients, is frequently underused, and only a...
5.
Heffler E, Blasi F, Paggiaro P, Canonica G
Adv Ther
. 2025 Jan;
42(2):1196-1206.
PMID: 39754702
Introduction: The burden of severe asthma on patients, especially on those with concomitant chronic rhinosinusitis with nasal polyps (CRSwNP), is substantial. Treatment intensification with oral corticosteroids is a common strategy...
6.
Brightling C, Marone G, Aegerter H, Chanez P, Heffler E, Pavord I, et al.
Eur Respir Rev
. 2024 Dec;
33(174.
PMID: 39694589
The Epithelial Science Expert Group convened on 18-19 October 2023, in Naples, Italy, to discuss the current understanding of the fundamental role of the airway epithelium in asthma and other...
7.
Costanzo G, Marchetti M, Ledda A, Sambugaro G, Bullita M, Paoletti G, et al.
Int J Mol Sci
. 2024 Dec;
25(23).
PMID: 39684326
Mast cells are immune system cells with the most disparate functions, but are also among the least understood. Mast cells are implicated in several known pathological processes, tissue homeostasis, and...
8.
Pace G, Giombi F, Pirola F, Cerasuolo M, Heffler E, Paoletti G, et al.
Ann Otol Rhinol Laryngol
. 2024 Nov;
134(3):201-210.
PMID: 39563019
Purpose: Although the effectiveness of molecular antibodies has been established, evidence is still lacking on objective predictors of response. The aim of this study was to assess whether the extent...
9.
Rodriguez-Otero N, Ramirez-Mateo E, Plana M, Heffler E, Antolin-Amerigo D
Curr Opin Allergy Clin Immunol
. 2024 Oct;
24(6):496-503.
PMID: 39364915
Purpose Of Review: Allergic rhinitis is a relevant and global health problem affecting up to 5-50% of the general population and its prevalence is increasing due to climate change and...
10.
Buchheit K, Shaw D, Chupp G, Lehtimaki L, Heffler E, Finney-Hayward T, et al.
Allergy
. 2024 Oct;
79(10):2662-2679.
PMID: 39359069
Interleukin (IL)-5 is the key cytokine in the maturation, activation, proliferation, migration and survival of eosinophils, which are key effector cells in many upper and lower airway diseases. Through its...