En-Shuo Liu
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Explore the profile of En-Shuo Liu including associated specialties, affiliations and a list of published articles.
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8
Citations
21
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0
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Recent Articles
1.
Liao T, Liu Y, Chen C, Wu B, Liu E, Hong S, et al.
Int J Biol Macromol
. 2025 Feb;
305(Pt 2):141003.
PMID: 39978521
4-1BB is a co-stimulatory immune checkpoint receptor that triggers CD8 T cell activation, leading to robust anti-tumor responses. Although antibodies targeting 4-1BB show promise in preclinical studies, systemic 4-1BB over-activation...
2.
Chang M, Lee C, Chang Y, Wu H, Wang Y, Chao H, et al.
Anal Chem
. 2025 Feb;
97(7):3872-3880.
PMID: 39939281
The dual luciferase reporter (DLR) assay is a well-known tool for gene expression analysis. Its ability to provide batch-to-batch, side-by-side normalization makes it a valuable method through which to explore...
3.
Ho K, Liu Y, Huang B, Hong S, Yang S, Liao T, et al.
Int J Biol Macromol
. 2025 Jan;
300:140138.
PMID: 39842595
Glycosidic switch liposome (GSL) technology efficiently encapsulates and stabilizes potent anticancer drugs in liposomes using a reversible glucuronide ester. Enzymatic hydrolysis of the glucuronide switch in target cell lysosomes produces...
4.
Liu Y, Liao T, Ho K, Liu E, Huang B, Hong S, et al.
Biomater Res
. 2024 Dec;
28:0112.
PMID: 39665081
The presence of anti-polyethylene glycol (anti-PEG) antibodies can hinder the therapeutic efficacy of PEGylated drugs. With the widespread use of a PEGylated coronavirus disease 2019 (COVID-19) messenger RNA vaccine (Comirnaty),...
5.
Ho K, Liu Y, Liao T, Liu E, Cheng T
Int J Nanomedicine
. 2024 Oct;
19:10045-10064.
PMID: 39371476
Polyethylene glycol (PEG)-modified nanoparticles (NPs) often struggle with reduced effectiveness against metastasis and liquid tumors due to limited tumor cell uptake and therapeutic efficacy. To address this, actively targeted liposomes...
6.
Chang M, Lee C, Liu E, Chao H, Wu H, Chang Y, et al.
Anal Chem
. 2023 Sep;
95(38):14341-14349.
PMID: 37715702
Reporter gene assays are essential for high-throughput analysis, such as drug screening or determining downstream signaling activation/inhibition. However, use of this technology has been hampered by the high cost of...
7.
Hsiao C, Meng J, Hong J, Ly X, Lin M, Chang C, et al.
Bioconjug Chem
. 2022 Nov;
33(11):2180-2188.
PMID: 36320124
Sensitive quantification of methoxy poly(ethylene glycol) (mPEG)-conjugated therapeutics for pharmacokinetic determination is critical for mPEGylated drug development. However, sensitive measurement of low-molecular-weight (lmw) mPEG compounds remains challenging due to epitope...
8.
Lin W, Ho K, Su H, Fang T, Tzou S, Chen I, et al.
Front Immunol
. 2022 Jan;
12:767868.
PMID: 34975855
Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune...
9.
Lin W, Lu Y, Huang B, Chuang C, Cheng Y, Chen I, et al.
Sci Rep
. 2021 Jul;
11(1):14846.
PMID: 34290297
Canakinumab is a fully human monoclonal antibody that specifically neutralizes human interleukin (IL)-1β and has been approved by the US Food and Drug Administration for treating different types of autoinflammatory...
10.
Ho K, Chen I, Cheng Y, Liao T, Liu E, Chen H, et al.
J Nanobiotechnology
. 2021 Jan;
19(1):16.
PMID: 33422061
Background: Tumor-targeted nanoparticles hold great promise as new tools for therapy of liquid cancers. Furthermore, the therapeutic efficacy of nanoparticles can be improved by enhancing the cancer cellular internalization. Methods:...