Emrin Horgusluoglu
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Explore the profile of Emrin Horgusluoglu including associated specialties, affiliations and a list of published articles.
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307
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Recent Articles
1.
Quinlan E, Baumgartner J, Chen W, Weber W, Horgusluoglu E, Edwards E
Front Psychol
. 2024 Oct;
15:1473735.
PMID: 39417020
Health restoration and disease prevention are important strategies to achieve health and well-being. This provides a conceptual overview of the key concepts of salutogenesis (health restoration), chronic stress, resilience, and...
2.
Horgusluoglu E, Neff R, Song W, Wang M, Wang Q, Arnold M, et al.
Alzheimers Dement
. 2021 Nov;
18(6):1260-1278.
PMID: 34757660
Metabolites, the biochemical products of the cellular process, can be used to measure alterations in biochemical pathways related to the pathogenesis of Alzheimer's disease (AD). However, the relationships between systemic...
3.
Wang M, Li A, Sekiya M, Beckmann N, Quan X, Schrode N, et al.
Neuron
. 2020 Nov;
109(2):257-272.e14.
PMID: 33238137
To identify the molecular mechanisms and novel therapeutic targets of late-onset Alzheimer's Disease (LOAD), we performed an integrative network analysis of multi-omics profiling of four cortical areas across 364 donors...
4.
Nho K, Kim S, Horgusluoglu E, Risacher S, Shen L, Kim D, et al.
BMC Med Genomics
. 2017 Jun;
10(Suppl 1):29.
PMID: 28589856
Background: The APOE ε4 allele is the most significant common genetic risk factor for late-onset Alzheimer's disease (LOAD). The region surrounding APOE on chromosome 19 has also shown consistent association...
5.
Kim D, Basile A, Bang L, Horgusluoglu E, Lee S, Ritchie M, et al.
BMC Med Inform Decis Mak
. 2017 May;
17(Suppl 1):61.
PMID: 28539126
Background: Rapid advancement of next generation sequencing technologies such as whole genome sequencing (WGS) has facilitated the search for genetic factors that influence disease risk in the field of human...
6.
Nho K, Horgusluoglu E, Kim S, Risacher S, Kim D, Foroud T, et al.
BMC Med Genomics
. 2016 Aug;
9 Suppl 1:30.
PMID: 27535542
Background: Pathogenic mutations in PSEN1 are known to cause familial early-onset Alzheimer's disease (EOAD) but common variants in PSEN1 have not been found to strongly influence late-onset AD (LOAD). The...
7.
Horgusluoglu E, Nudelman K, Nho K, Saykin A
Am J Med Genet B Neuropsychiatr Genet
. 2016 Feb;
174(1):93-112.
PMID: 26879907
New neurons are generated throughout adulthood in two regions of the brain, the olfactory bulb and dentate gyrus of the hippocampus, and are incorporated into the hippocampal network circuitry; disruption...
8.
Nho K, Ramanan V, Horgusluoglu E, Kim S, Inlow M, Risacher S, et al.
J Alzheimers Dis
. 2015 Feb;
45(4):1197-206.
PMID: 25690665
Depressive symptoms are common in older adults and are particularly prevalent in those with or at elevated risk for dementia. Although the heritability of depression is estimated to be substantial,...
9.
Ahlfeld S, Gao Y, Wang J, Horgusluoglu E, Bolanis E, Clapp D, et al.
Birth Defects Res A Clin Mol Teratol
. 2013 Jun;
97(6):373-85.
PMID: 23723163
Background: Extreme preterm birth exposes the saccular lung to multiple teratogens, which ultimately retard alveolar development. Specifically, therapeutic high level oxygen supplementation adversely affects the premature lungs and results in...
10.
Sirma S, Agaoglu L, Yildiz I, Cayli D, Horgusluoglu E, Anak S, et al.
Pediatr Blood Cancer
. 2004 Sep;
43(5):568-70.
PMID: 15382274
Background: NAD(P)H:quinone oxidoreductase1 (NQO1) is a two-electron reductase that detoxifies quinones derived from the oxidation of phenolic metabolites of benzene. Exposure to benzene metabolites increases the risk of hematotoxicity and...