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Emmanuelle Kieffer

Explore the profile of Emmanuelle Kieffer including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 155
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Recent Articles
1.
Van Der Kelen A, Okutman O, Javey E, Serdarogullari M, Janssens C, Ghosh M, et al.
Hum Reprod Update . 2022 Dec; 29(2):218-232. PMID: 36571510
Background: As in other domains of medicine, high-throughput sequencing methods have led to the identification of an ever-increasing number of gene variants in the fields of both male and female...
2.
Kieffer E, Nicod J, Gardes N, Kastner C, Becker N, Celebi C, et al.
Eur J Hum Genet . 2015 May; 24(2):221-7. PMID: 25966634
Fragile X syndrome (FraX) is caused by the expansion of an unstable CGG repeat located in the Fragile X mental retardation 1 gene (FMR1) gene. Preimplantation genetic diagnosis (PGD) can...
3.
Tarabay Y, Kieffer E, Teletin M, Celebi C, Van Montfoort A, Zamudio N, et al.
Hum Reprod . 2013 May; 28(8):2201-14. PMID: 23674551
Study Question: What is the consequence of Tex19.1 gene deletion in mice? Summary Answer: The Tex19.1 gene is important in spermatogenesis and placenta-supported development. What Is Known Already: Tex19.1 is...
4.
Celebi C, Van Montfoort A, Skory V, Kieffer E, Kuntz S, Mark M, et al.
J Reprod Dev . 2012 Mar; 58(3):360-5. PMID: 22447323
We have previously suggested that TEX19, a mammalian-specific protein of which two paralogs exist in rodents, could be implicated in stem cell self-renewal and pluripotency. We have established here the...
5.
Bouakaze C, Eschbach J, Fouquerel E, Gasser I, Kieffer E, Krieger S, et al.
Biochem Mol Biol Educ . 2011 May; 38(5):296-302. PMID: 21567848
The Strasbourg University PhD school in Life and Health Sciences launched an initiative called "OpenLAB." This project was developed in an effort to help high school teenagers understand theoretical and...
6.
Kieffer E, Kuntz S, Viville S
Med Sci (Paris) . 2010 Oct; 26(10):848-54. PMID: 20929676
More than 20 years ago, the finding of a population of cells with the ability of self-renewal and differentiation inside teratocarcinomas (embryonic carcinoma cells) would allow their direct derivation from...
7.
Ciaudo C, Servant N, Cognat V, Sarazin A, Kieffer E, Viville S, et al.
PLoS Genet . 2009 Aug; 5(8):e1000620. PMID: 19714213
Embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of the mammalian blastocyst. Cellular differentiation entails loss of pluripotency and gain of lineage-specific characteristics. However, the...
8.
Madan B, Madan V, Weber O, Tropel P, Blum C, Kieffer E, et al.
Mol Cell Biol . 2009 Apr; 29(11):3186-203. PMID: 19332562
Dppa4 (developmental pluripotency-associated 4) has been identified in several high-profile screens as a gene that is expressed exclusively in pluripotent cells. It encodes a nuclear protein with an SAP-like domain...
9.
Buhr N, Carapito C, Schaeffer C, Kieffer E, Van Dorsselaer A, Viville S
Electrophoresis . 2008 May; 29(11):2381-90. PMID: 18449859
Embryonic stem cells (ESCs) and embryonic germ cells (EGCs) provide exciting models for understanding the underlying mechanisms that make a cell pluripotent. Indeed, such understanding would enable dedifferentiation and reprogrammation...
10.
Kuntz S, Kieffer E, Bianchetti L, Lamoureux N, Fuhrmann G, Viville S
Stem Cells . 2007 Dec; 26(3):734-44. PMID: 18096721
Although the properties of embryonic stem (ES) cells make these cells very attractive in the field of replacement therapy, the molecular mechanisms involved in the maintenance of their pluripotency are...