Emmanuelle Bouzigon
Overview
Explore the profile of Emmanuelle Bouzigon including associated specialties, affiliations and a list of published articles.
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63
Citations
2106
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Recent Articles
1.
Mauclin M, Guillien A, Niespodziana K, Boudier A, Schlederer T, Bajic M, et al.
J Allergy Clin Immunol Glob
. 2024 Nov;
4(1):100342.
PMID: 39507925
Background: Viral infections in childhood, especially to rhinovirus (RV) and respiratory syncytial virus (RSV), are associated with asthma inception and exacerbation. However, little is known about the role of RV-...
2.
Suzuki Y, Menager H, Brancotte B, Vernet R, Nerin C, Boetto C, et al.
HGG Adv
. 2024 Jun;
5(3):100319.
PMID: 38872309
Since the first genome-wide association studies (GWASs), thousands of variant-trait associations have been discovered. However, comprehensively mapping the genetic determinant of complex traits through univariate testing can require prohibitive sample...
3.
Guillien A, Niespodziana K, Mauclin M, Boudier A, Varraso R, Leynaert B, et al.
Front Immunol
. 2024 Mar;
15:1355214.
PMID: 38500884
Introduction: Exposure to respiratory viruses is a significant cause of morbidity and affects virus-specific antibody levels. Little is known about determinants associated with immune response to these viruses. We aimed...
4.
Visona G, Bouzigon E, Demenais F, Schweikert G
Brief Bioinform
. 2024 Feb;
25(2).
PMID: 38340090
Motivation: Genome-wide association studies (GWAS) have enabled large-scale analysis of the role of genetic variants in human disease. Despite impressive methodological advances, subsequent clinical interpretation and application remains challenging when...
5.
Suzuki Y, Menager H, Brancotte B, Vernet R, Nerin C, Boetto C, et al.
bioRxiv
. 2023 Nov;
PMID: 37961722
Since the first Genome-Wide Association Studies (GWAS), thousands of variant-trait associations have been discovered. However, the sample size required to detect additional variants using standard univariate association screening is increasingly...
6.
Margaritte-Jeannin P, Vernet R, Budu-Aggrey A, Ege M, Madore A, Linhard C, et al.
Allergy Asthma Immunol Res
. 2023 Nov;
15(6):779-794.
PMID: 37957795
Purpose: Numerous genes have been associated with allergic diseases (asthma, allergic rhinitis, and eczema), but they explain only part of their heritability. This is partly because most previous studies ignored...
7.
Vernet R, Matran R, Zerimech F, Madore A, Lavoie M, Gagnon P, et al.
J Allergy Clin Immunol
. 2022 Jun;
150(5):1168-1177.
PMID: 35671886
Background: Eosinophils play a key role in the asthma allergic response by releasing cytotoxic molecules such as eosinophil cationic protein (ECP) and eosinophil-derived neurotoxin (EDN) that generate epithelium damages. Objective:...
8.
Orsi L, Margaritte-Jeannin P, Andrianjafimasy M, Dumas O, Mohamdi H, Bouzigon E, et al.
Antioxidants (Basel)
. 2022 May;
11(5).
PMID: 35624665
Oxidative stress (OS) is the main pathophysiological mechanism involved in several chronic diseases, including asthma. Fluorescent oxidation products (FlOPs), a global biomarker of damage due to OS, is of growing...
9.
Madore A, Bosse Y, Margaritte-Jeannin P, Vucic E, Lam W, Bouzigon E, et al.
BMC Pulm Med
. 2022 Apr;
22(1):155.
PMID: 35461280
Background: Asthma, lung cancer (LC) and chronic obstructive pulmonary disease (COPD) are three respiratory diseases characterized by complex mechanisms underlying and genetic predispositions, with asthma having the highest calculated heritability....
10.
Bouzigon E, Barouki R
Rev Prat
. 2021 Nov;
71(7):727-728.
PMID: 34792907
THE CASE FOR EPIGENETIC ALTERATIONS The mechanisms of the long-term impacts of exposure to chemical substances remain poorly understood. While genotoxic and mutagenic effects have been well characterized, epigenetic mechanisms...