Emmanuel Varesio
Overview
Explore the profile of Emmanuel Varesio including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
53
Citations
659
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Abouir K, Varesio E, Deglon J, Samer C, Daali Y
Basic Clin Pharmacol Toxicol
. 2024 Oct;
135(6):755-766.
PMID: 39385496
Omeprazole (OME) is a CYP2C19 phenotyping probe, marketed as a racemic (S)/(R) mixture or as an S-enantiomer. Both CYP2C19 and CYP3A4 enzymes mediate (R)-OME hydroxylation to (R)-5-hydroxyomeprazole, while (S)-OME is...
2.
Abouir K, Samer C, Landry R, Varesio E, Daali Y
J Chromatogr B Analyt Technol Biomed Life Sci
. 2023 Dec;
1232:123962.
PMID: 38096743
Omeprazole (OME) is a widely used gastric proton pump inhibitor, marketed as a racemic mixture comprising (S)- and (R)-enantiomers, with distinct pharmacokinetic profiles. OME is primarily metabolized by the cytochrome...
3.
Cionca N, Meyer J, Michalet S, Varesio E, Hashim D
Clin Oral Investig
. 2023 Jun;
27(8):4715-4726.
PMID: 37270723
Objectives: Metallic particles are detected in different sites of the oral cavity, mainly in patients with peri-implantitis lesions. The aim of this pilot study was to analyze the levels of...
4.
Howieson V, Zeng J, Kloehn J, Spry C, Marchetti C, Lunghi M, et al.
Int J Parasitol Drugs Drug Resist
. 2023 Apr;
22:1-8.
PMID: 37004488
Toxoplasma gondii is a pervasive apicomplexan parasite that can cause severe disease and death in immunocompromised individuals and the developing foetus. The treatment of toxoplasmosis often leads to serious side...
5.
Sansaloni-Pastor S, Varesio E, Lange N
J Photochem Photobiol B
. 2022 Jun;
233:112484.
PMID: 35671620
5-ALA-mediated photodynamic therapy (PDT) has been developed around the heme biosynthesis physiological pathway. It is based on the external supplementation of 5 aminolevulinic acid (5-ALA), increasing the activity of the...
6.
Lunghi M, Kloehn J, Krishnan A, Varesio E, Vadas O, Soldati-Favre D
Nat Commun
. 2022 Jan;
13(1):345.
PMID: 35039477
Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms synthesize CoA, many, including humans, are unable to produce its...
7.
Kloehn J, Lunghi M, Varesio E, Dubois D, Soldati-Favre D
Metabolites
. 2021 Aug;
11(8).
PMID: 34436417
Apicomplexan parasites are responsible for devastating diseases, including malaria, toxoplasmosis, and cryptosporidiosis. Current treatments are limited by emerging resistance to, as well as the high cost and toxicity of existing...
8.
Krishnan A, Kloehn J, Lunghi M, Chiappino-Pepe A, Waldman B, Nicolas D, et al.
Cell Host Microbe
. 2020 Jan;
27(2):290-306.e11.
PMID: 31991093
To survive and proliferate in diverse host environments with varying nutrient availability, the obligate intracellular parasite Toxoplasma gondii reprograms its metabolism. We have generated and curated a genome-scale metabolic model...
9.
Bruderer T, Varesio E, Hidasi A, Duchoslav E, Burton L, Bonner R, et al.
Anal Bioanal Chem
. 2018 Feb;
410(7):1873-1884.
PMID: 29411086
High-quality mass spectral libraries have become crucial in mass spectrometry-based metabolomics. Here, we investigate a workflow to generate accurate mass discrete and composite spectral libraries for metabolite identification and for...
10.
Bruderer T, Varesio E, Hopfgartner G
J Chromatogr B Analyt Technol Biomed Life Sci
. 2017 Aug;
1071:3-10.
PMID: 28780068
The application of predicted LC retention time to support metabolite identification was evaluated for a metabolomics MS/MS database containing 532 compounds representative for the major human metabolite classes. LC retention...