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Emma R Hinkle

Explore the profile of Emma R Hinkle including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 55
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Recent Articles
1.
Hinkle E, Blue R, Tsai Y, Combs M, Davi J, Coffey A, et al.
Commun Biol . 2022 Oct; 5(1):1080. PMID: 36216866
No abstract available.
2.
Hinkle E, Blue R, Tsai Y, Combs M, Davi J, Coffey A, et al.
Commun Biol . 2022 Sep; 5(1):987. PMID: 36123433
Alternative splicing is an RNA processing mechanism involved in skeletal muscle development and pathology. Muscular diseases exhibit splicing alterations and changes in mechanobiology leading us to investigate the interconnection between...
3.
Gentile G, Gamarra J, Engels N, Blue R, Hoerr I, Wiedner H, et al.
FASEB J . 2022 Jul; 36(8):e22441. PMID: 35816155
Vesicle-mediated transport is necessary for maintaining cellular homeostasis and proper signaling. The synaptosome-associated protein 23 (SNAP23) is a member of the SNARE protein family and mediates the vesicle docking and...
4.
Hinkle E, Wiedner H, Torres E, Jackson M, Black A, Blue R, et al.
RNA . 2022 Jan; 28(4):523-540. PMID: 35082143
Alternative splicing transitions occur during organ development, and, in numerous diseases, splicing programs revert to fetal isoform expression. We previously found that extensive splicing changes occur during postnatal mouse heart...
5.
Schertzer M, Thulson E, Braceros K, Lee D, Hinkle E, Murphy R, et al.
RNA . 2019 May; 25(8):1047-1058. PMID: 31101683
We describe the development and application of a novel series of vectors that facilitate CRISPR-Cas9-mediated genome editing in mammalian cells, which we call CRISPR-Bac. CRISPR-Bac leverages the piggyBac transposon to...
6.
Hinkle E, Wiedner H, Black A, Giudice J
Transcription . 2018 Dec; 10(1):1-20. PMID: 30556762
RNA processing encompasses the capping, cleavage, polyadenylation and alternative splicing of pre-mRNA. Proper muscle development relies on precise RNA processing, driven by the coordination between RNA-binding proteins. Recently, skeletal muscle...