Emma Derrett-Smith
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Explore the profile of Emma Derrett-Smith including associated specialties, affiliations and a list of published articles.
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16
Citations
186
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Recent Articles
1.
Denton C, De Lorenzis E, Roblin E, Goldman N, Alcacer-Pitarch B, Blamont E, et al.
Rheumatology (Oxford)
. 2024 Sep;
63(11):2956-2975.
PMID: 39255973
This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience,...
2.
Denton C, De Lorenzis E, Roblin E, Goldman N, Alcacer-Pitarch B, Blamont E, et al.
Rheumatology (Oxford)
. 2024 Sep;
63(11):2948-2955.
PMID: 39255970
This guideline was developed according to the British Society for Rheumatology Guidelines Protocol by a Guideline Development Group comprising healthcare professionals with expertise in SSc and people with lived experience,...
3.
De Lorenzis E, Kakkar V, Di Donato S, Wilson M, Barnes T, Denton C, et al.
RMD Open
. 2024 Jan;
10(1).
PMID: 38216288
Background: Hand involvement is an early manifestation of systemic sclerosis (SSc), culprit of diagnosis and classification, and recognised major driver of disability. Impairment of hand function burdens both limited and...
4.
Denton C, De Lorenzis E, Roblin E, Goldman N, Alcacer-Pitarch B, Blamont E, et al.
Rheumatol Adv Pract
. 2023 Mar;
7(1):rkad022.
PMID: 36923262
This guideline will provide a practical roadmap for management of SSc that builds upon the previous treatment guideline to incorporate advances in evidence-based treatment and increased knowledge about assessment, classification...
5.
Clark K, Csomor E, Campochiaro C, Galwey N, Nevin K, Morse M, et al.
Lancet Rheumatol
. 2022 Nov;
4(7):e507-e516.
PMID: 36404995
Background: Skin fibrosis is a hallmark feature of systemic sclerosis. Skin biopsy transcriptomics and blister fluid proteomics give insight into the local environment of the skin. We have integrated these...
6.
Franks J, Toledo D, Martyanov V, Wang Y, Huang S, Wood T, et al.
Rheumatology (Oxford)
. 2022 Jun;
62(1):19-28.
PMID: 35751592
Objectives: Four intrinsic molecular subsets (inflammatory, fibroproliferative, limited, normal-like) have previously been identified in SSc and are characterized by unique gene expression signatures and pathways. The intrinsic subsets have been...
7.
Sahbudin I, Singh R, de Pablo P, Rankin E, Rhodes B, Justice E, et al.
Rheumatology (Oxford)
. 2022 Apr;
62(3):1057-1068.
PMID: 35412605
Objectives: The value of US-defined tenosynovitis in predicting the persistence of inflammatory arthritis is not well described. In particular, the predictive utility of US-defined tenosynovitis of larger tendons is yet...
8.
Wasson C, Caballero-Ruiz B, Gillespie J, Derrett-Smith E, Mankouri J, Denton C, et al.
Cells
. 2022 Feb;
11(3).
PMID: 35159339
Chloride intracellular channel 4 (CLIC4) is a recently discovered driver of fibroblast activation in Scleroderma (SSc) and cancer-associated fibroblasts (CAF). CLIC4 expression and activity are regulated by TGF-β signalling through...
9.
Derrett-Smith E, Clark K, Shiwen X, Abraham D, Hoyles R, Lacombe O, et al.
Arthritis Res Ther
. 2021 Sep;
23(1):234.
PMID: 34488870
Background: The TβRII∆k-fib transgenic (TG) mouse model of scleroderma replicates key fibrotic and vasculopathic complications of systemic sclerosis through fibroblast-directed upregulation of TGFβ signalling. We have examined peroxisome proliferator-activated receptor...
10.
Spierings J, Nihtyanova S, Derrett-Smith E, Clark K, van Laar J, Ong V, et al.
Rheumatology (Oxford)
. 2021 Jul;
61(5):1948-1956.
PMID: 34314500
Objectives: The aim of this study was to explore outcomes in a cohort of dcSSc patients fulfilling eligibility criteria for stem cell transplantation (SCT) studies but receiving standard immunosuppression. Methods:...