Emilia Mira
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Explore the profile of Emilia Mira including associated specialties, affiliations and a list of published articles.
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30
Citations
1219
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Recent Articles
1.
Nonnast E, Mira E, Manes S
J Transl Med
. 2025 Jan;
23(1):83.
PMID: 39825429
Laminins (LMs) are a family of heterotrimeric glycoproteins that form the structural foundation of basement membranes (BM). By acting as molecular bridges between cells and the extracellular matrix (ECM) through...
2.
Nonnast E, Mira E, Manes S
Biochim Biophys Acta Rev Cancer
. 2024 Sep;
1879(6):189181.
PMID: 39299492
Laminins (LMs) constitute a family of heterotrimeric glycoproteins essential for the formation of basement membranes (BM). They act as molecular bridges between cells and the extracellular matrix (ECM), thereby transmitting...
3.
Carmona-Rodriguez L, Martinez-Rey D, Martin-Gonzalez P, Franch M, Sorokin L, Mira E, et al.
Cancers (Basel)
. 2022 Mar;
14(5).
PMID: 35267534
The balance between laminin isoforms containing the α5 or the α4 chain in the endothelial basement membrane determines the site of leukocyte diapedesis under inflammatory conditions. Extracellular superoxide dismutase (SOD3)...
4.
Martinez-Rey D, Carmona-Rodriguez L, Fernandez-Acenero M, Mira E, Manes S
Front Immunol
. 2020 Nov;
11:579552.
PMID: 33250894
Tumor-infiltrating lymphocytes (TILs) are major players in the immune-mediated control of cancer and the response to immunotherapy. In primary cancers, however, TILs are commonly absent, suggesting T-cell entry into the...
5.
Carmona-Rodriguez L, Martinez-Rey D, Mira E, Manes S
Oncoimmunology
. 2020 Sep;
9(1):1794163.
PMID: 32934887
Abbreviations: AJ, adherens junction; EC, endothelial cell; EC-BM, endothelial basement membrane; HIF, hypoxia-inducible factor; ICAM-1, intercellular adhesion molecule-1; LAMA4, laminin-α4; SOD3, superoxide dismutase-3; TME, tumor microenvironment; VCAM-1, vascular cell adhesion...
6.
Carmona-Rodriguez L, Martinez-Rey D, Fernandez-Acenero M, Gonzalez-Martin A, Paz-Cabezas M, Rodriguez-Rodriguez N, et al.
J Immunother Cancer
. 2020 Jun;
8(1).
PMID: 32591431
Background: Tumor-infiltrating lymphocytes (TILs), mainly CD8 cytotoxic T lymphocytes (CTL), are linked to immune-mediated control of human cancers and response to immunotherapy. Tumors have nonetheless developed specific mechanisms that selectively...
7.
Mira E, Carmona-Rodriguez L, Perez-Villamil B, Casas J, Fernandez-Acenero M, Martinez-Rey D, et al.
Nat Commun
. 2018 Feb;
9(1):575.
PMID: 29422508
One drawback of chemotherapy is poor drug delivery to tumor cells, due in part to hyperpermeability of the tumor vasculature. Extracellular superoxide dismutase (SOD3) is an antioxidant enzyme usually repressed...
8.
Mira E, Carmona-Rodriguez L, Tardaguila M, Azcoitia I, Gonzalez-Martin A, Almonacid L, et al.
Oncotarget
. 2013 Dec;
4(12):2288-301.
PMID: 24317954
Beyond their ability to inhibit cholesterol biosynthesis, the statins have pleiotropic effects that include anti-inflammatory and immunomodulatory activities. Statins could have clinical utility, alone or in combination with other chemotherapeutics,...
9.
Bolos V, Mira E, Martinez-Poveda B, Luxan G, Canamero M, Martinez-A C, et al.
Breast Cancer Res
. 2013 Jul;
15(4):R54.
PMID: 23826634
Introduction: Dysregulated NOTCH receptor activity has been implicated in breast cancer but the mechanisms by which NOTCH contributes to transformation are not yet clear, as it has context-dependent effects on...
10.
Tardaguila M, Mira E, Garcia-Cabezas M, Feijoo A, Quintela-Fandino M, Azcoitia I, et al.
Cancer Res
. 2013 May;
73(14):4461-73.
PMID: 23720051
Chemokines are relevant molecules in shaping the tumor microenvironment, although their contributions to tumorigenesis are not fully understood. We studied the influence of the chemokine CX3CL1/fractalkine in de novo breast...